18 Research Administration jobs in South Africa

Clinical Research Associate - Johannesburg

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative treatments and therapies.

What you will be doing

• Conducting site qualification, initiation, monitoring, and close-out visits for clinical trials.

• Ensuring protocol compliance, data integrity, and patient safety throughout the trial process.

• Collaborating with investigators and site staff to facilitate smooth study conduct.

• Performing data review and resolution of queries to maintain high-quality clinical data.

• Contributing to the preparation and review of study documentation, including protocols and clinical study reports

Your profile

• Bachelor's degree in a scientific or healthcare-related field.

• Minimum of 2 years of experience as a Clinical Research Associate.

• In-depth knowledge of clinical trial processes, regulations, and ICH-GCP guidelines.

• Strong organizational and communication skills, with attention to detail.

• Ability to work independently and collaboratively in a fast-paced environment.

• Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver's license

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

Visit our

careers site

to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Job Title: Clinical Research Associate (CRA)

Location: Cape Town, South Africa

Company: ICON Strategic Solutions – FSP

As a Clinical Research Associate, Your Primary Focus Will Be On The End-to-end Management Of Clinical Trials At Assigned Study Sites. You Will

• Collaborate closely with the local study team to meet study goals, timelines, and site commitments.
• Serve as the primary point of contact for study sites, overseeing the preparation, initiation, monitoring, and closure of clinical trials.
• Ensure compliance with international guidelines (ICH-GCP) and local regulations to guarantee the integrity and safety of the study.
• Proactively identify and resolve study-related issues, escalating as necessary to ensure smooth site performance.
• Conduct monitoring visits (both on-site and remote) and manage essential study documentation.
• Assist in site training, patient recruitment, data management, and quality control to ensure the study runs efficiently.
• Maintain accurate and up-to-date records in CTMS and ensure study sites remain inspection-ready at all times.

We're Searching For a Highly Motivated Individual With

• A minimum of 3 years of experience as a CRA or in a similar role, preferably across multiple therapeutic areas.CV and Respiratory are an advantage.
• University degree in Health Science, or a related field.
• To be based in Cape Town.
• Compliance Knowledge: Strong knowledge of ICH-GCP guidelines and local regulatory requirements.
• Communication Skills: Excellent interpersonal and communication skills, with the ability to build strong relationships with investigators and site staff.
• Problem-Solving: A proactive approach to identifying and resolving issues while maintaining a high level of attention to detail.
• Adaptability: The ability to work effectively in a fast-paced and dynamic environment, managing multiple priorities with precision.

What ICON Can Offer You
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our Benefits Examples Include

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs
• Competitive retirement planning offerings to maximise savings and plan with confidence for the years ahead
• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others

Visit our careers website to read more about the benefits of working at ICON:

At ICON, diversity, inclusion & belonging are fundamental to our culture and values. Our rich diversity makes us more innovative which helps us better serve our people, patients, customers, and our communities. We're proud of our diverse workforce and the work we've done to become a more inclusive organisation. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know through the form below.

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Clinical Research Associate - Johannesburg

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative treatments and therapies.

What You Will Be Doing

• Conducting site qualification, initiation, monitoring, and close-out visits for clinical trials.
• Ensuring protocol compliance, data integrity, and patient safety throughout the trial process.
• Collaborating with investigators and site staff to facilitate smooth study conduct.
• Performing data review and resolution of queries to maintain high-quality clinical data.
• Contributing to the preparation and review of study documentation, including protocols and clinical study reports

Your profile

• Bachelor's degree in a scientific or healthcare-related field.
• Minimum of 2 years of experience as a Clinical Research Associate.
• In-depth knowledge of clinical trial processes, regulations, and ICH-GCP guidelines.
• Strong organizational and communication skills, with attention to detail.
• Ability to work independently and collaboratively in a fast-paced environment.
• Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver's license

What ICON Can Offer You
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our Benefits Examples Include

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply

CAPRISA is an award-winning global research organisation located on the campus of the Nelson R Mandela School of Medicine in Durban, South Africa and undertakes research in HIV, TB and Covid at four clinical research sites in KwaZulu-Natal. CAPRISA's goal is to undertake globally relevant and locally responsive research that contributes to understanding HIV Vaccines and Pathogenesis, Prevention and Epidemiology, the links between Tuberculosis and AIDS treatment and Covid-19. CAPRISA is a UNAIDS Collaborating Centre for HIV Research and Policy and is recognised as a DSI-NRF Centre of Excellence in HIV Prevention and hosts the SAMRC HIV-TB Pathogenesis and Treatment Research Unit.

The successful incumbent will join the CAPRISA Gates Foundation Vaginal Microbiome Clinical Trials Unit (VM-CTU) and will be based at the CAPRISA Headquarters in Durban.

• A bachelor's degree in a health-related or life sciences discipline (e.g., Pharmacy, Nursing, Medical Sciences, Clinical Research, or equivalent).
• At least 2–3 years of experience monitoring clinical trials with knowledge of clinical trials operations, preferably early-phase (Phase I/II) studies.
• Solid knowledge of SA GCP guidelines, ICH-GCP guidelines, South African Ethics in Health Research Guidelines, SAHPRA and international regulatory requirements.
• Prior experience in monitoring and/or trial coordination, within an academic or as a CRA in industry-sponsored trial setting.
• Strong understanding of investigational product accountability, safety reporting, and protocol compliance.
• Proficiency in MS Office (Word, Excel, PowerPoint, Outlook) and familiarity with electronic data capture (EDC) systems.
• Experience working within a multidisciplinary research environment is an advantage.

• Assume the role of regional monitor for all trials conducted in the VM-CTU for an estimated 5 trials per annum.
• Develop and maintain Standard Operating Procedures relevant to the portfolio.
• Create trial monitoring plans in conjunction with the trial sponsor representatives.
• Conduct study initiation visits for each new trial protocol to assess site readiness for study activation.
• Conduct trial monitoring (clinic, laboratory and pharmacy) to ensure compliance with study protocols, SOPs, ICH-GCP, and local regulatory requirements.
• Review case report forms (CRFs), source documents, and data entry to verify accuracy, completeness, and timeliness.
• Monitor and track protocol deviations, adverse events (AEs/SAEs), and data queries.
• Review essential study documentation, including trial master file (eTMF) and investigator site file (eISF).
• Prepare monitoring reports, progress updates, and assist with audits and inspection preparation.
• Contribute to quality assurance initiatives and continuous improvement of trial conduct at the unit.
• Support close-out activities, ensuring data integrity and regulatory compliance are maintained throughout the trial lifecycle.

Role Description

This is a full-time, on-site role for a Clinical Research Associate based in Durban. The Clinical Research Associate will oversee the daily operations of clinical trials, ensure compliance with protocols, and manage research activities. Responsibilities include coordinating with clinical trial sites, monitoring the progress of studies, and maintaining accurate documentation. The role involves close collaboration with other clinical research professionals to ensure the integrity and quality of the research data.

Responsibilities:

• Assume the role of regional monitor for all trials conducted in the VM-CTU for an estimated 5 trials per annum.
• Develop and maintain Standard Operating Procedures relevant to the portfolio.
• Create trial monitoring plans in conjunction with the trial sponsor representatives.
• Conduct study initiation visits for each new trial protocol to assess site readiness for study activation.
• Conduct trial monitoring (clinic, laboratory and pharmacy) to ensure compliance with study protocols, SOPs, ICH-GCP, and local regulatory requirements.
• Review case report forms (CRFs), source documents, and data entry to verify accuracy, completeness, and timeliness.

Qualifications

• A bachelor's degree in a health-related or life sciences discipline (e.g., Pharmacy, Nursing, Medical Sciences, Clinical Research, or equivalent).
• At least 2–3 years of experience monitoring clinical trials with knowledge of clinical trials operations, preferably early-phase (Phase I/II) studies.
• Solid knowledge of SA GCP guidelines, ICH-GCP guidelines, South African Ethics in Health Research Guidelines, SAHPRA and international regulatory requirements.
• Prior experience in monitoring and/or trial coordination, within an academic or as a CRA in industry-sponsored trial setting.
• Strong understanding of investigational product accountability, safety reporting, and protocol compliance.
• Proficiency in MS Office (Word, Excel, PowerPoint, Outlook) and familiarity with electronic data capture (EDC) systems.
• Experience working within a multidisciplinary research environment is an advantage.

Position
: Clinical Research Nurse

Location:
Bloemfontein – Office based

Job Type:
Full-time

Division:
Clinic

Closing date:
19 September 2025

About Us:

Are you ready to be part of a pioneering force in clinical research? With a rich history dating back to 1974, FARMOVS has been at the forefront of accelerating product development through innovative ICH GCP compliant phase 1-2a clinical trials. Having conducted over 3000 trials at our esteemed facility, we offer unmatched expertise and experience in the field.

At FARMOVS, we pride ourselves on our extensive capabilities, including a GLP certified bioanalytical laboratory, registered pharmacy, and a cutting-edge 98-bed clinic equipped with an ISO 15189 accredited clinical laboratory.

Together, we are pushing the boundaries of medical science and improving lives through groundbreaking clinical research. We collaborate with top-tier institutions and sponsors to conduct clinical trials that pave the way for new treatments and therapies.

Located on the vibrant campus of the University of the Free State in Bloemfontein, central South Africa, FARMOVS offers a dynamic and stimulating work environment.

Position overview:

Are you a compassionate, detail-oriented nursing professional with a passion for advancing healthcare? Then this is the job for you We are seeking a skilled Clinical Research Nurse to join our dynamic team at FARMOVS. A Clinical Research Nurse plays a pivotal role in the healthcare and research sector by coordinating and managing clinical trials according to clinical study protocols, South African and ICH GCP Guidelines and SOPs and ensuring the integrity of the research process while prioritizing patient care.

What we are looking for:

Key Accountabilities:

• Review protocol, Clinical Report Form (CRF) and other related functions (e.g. data transcribing).
• Assist in the recruitment of Trial participants,
• Preparation for execution of studies (e.g. prepare source data), screening and execution of studies.
• Ensure accurate collection, recording, and reporting of trial data in compliance with ethical and regulatory standards.
• Support and educate participants about clinical trials while safeguarding their rights and wellbeing.
• Perform verification and operational QC procedures.
• Working on nominated projects / ad hoc project work and any other protocol specific procedures applicable for which training is given.
• Willing to work flexible hours in terms of day shift and possible night shift hours.

Skills:

• Thorough knowledge of applicable international and local guidelines and regulations (e.g. South African & ICH GCP), SOP's and Basic Life Support;
• Excellent interpersonal, verbal and written communication skills;
• Ability to manage multiple and varied tasks with enthusiasm and prioritize workload with attention to detail;
• Ability to motivate volunteers to be reliable and responsible whilst participating in trials;
• Self-motivated with a willingness to accept responsibility and challenges;
• Ability to work in a team and have a flexible attitude;
• Computer skills; ability to use MS Word, Excel, Outlook;
• Accurate execution of protocol related procedures;
• Able to work independently and with initiative.

Education and Experience:

• B Degree/Diploma in nursing
• Registration with SANC
• Current BLS or ACLS certification
• 2 years' experience as a registered nurse

Why Join Us?

At FARMOVS, you will be part of a collaborative team working on innovative projects that make a real difference. We value teamwork, quality, and a commitment to excellence. If you are ready to take on new challenges and grow your career in Information Technology in the Clinical research environment, we would love to hear from you

How to Apply:

If you are eager to contribute to groundbreaking clinical research and interested in joining our dynamic team, please send your CV to and we will contact you. Should you not receive a personal response from us within two to three weeks after the closing date of the vacancy, you can consider your application to have been unsuccessful.

FARMOVS is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Title of Position

Specialist: e-Research Systems Administration

Post Number

9089

Faculty/Department

University of the Western Cape -> Deputy Vice-Chancellor: Research & Innovation -> e-Research Office

Type of Position

Permanent - Full Time

Length of Contract Period

Location

Main Campus - Bellville, WC ZA (Primary)

Closing Date

31/10/2025

Role Clarification & Key Performance Areas
The University of the Western Cape has over the past few years steadily become one of the research-led teaching and learning universities in South Africa, with the capacity to produce and advance new knowledge in recognised research strength and the translation of this knowledge through innovation endeavours. In order to accelerate research, the University established the eResearch Unit in the office of the DVC (Research and Innovation) in 2019. This unit supports and promotes the use of advanced information technologies to enable better, faster and higher-impact research at UWC.

An exciting opportunity exists in the eResearch Unit for a suitably qualified candidate to the position of Specialist: eResearch Systems Administration. The appointed person will be responsible for managing High Performance Computing (HPC), cloud-integrated systems, and Research Data Management (RDM) solutions to deliver scalable, reliable computational resources. The role involves installing, configuring, operating, and maintaining Linux, Windows, and application systems that support research infrastructure. Key tasks include managing research software environments, monitoring system health, troubleshooting, and ensuring optimal performance and security. The Specialist: eResearch Systems Administration applies predictive analytics to optimize resource usage and maintain compliance with cybersecurity and regulatory standards. Additionally, the role provides technical consultation, user training, and documentation, while implementing improvements that align with the eResearch Office's strategic objectives to support computational and data-driven research.

The successful candidate will be responsible for, but not limited to, the following key areas:

• High Performance and Cloud-integrated Computing infrastructure management
• Provisioning and lifecycle management of research software environments
• Research data management infrastructure support
• User access management and authentication on eResearch infrastructure
• Predictive system monitoring and intelligent resource optimization
• Researcher enablement, technical consulting, and capacity building
• Assume other ad hoc tasks related to the eResearch Office's mission

Minimum Requirements
Minimum Requirements
:(Qualification & Experience)

• A relevant Honours degree or a relevant equivalent qualification at NQF8 in Computer Science, Information Technology or Computer Engineering
• A minimum of 5 years of experience in systems administration with a proven track record managing Linux- and Windows-based servers, storage systems, and enterprise IT environments.
• Practical experience with technologies such as SLURM, OpenStack, AWS, or Azure for research computing.
• Practical experience with RDM platforms such as iRODS, YoDa, or equivalent, and familiarity with research data capture tools like REDCap. A strong understanding of FAIR data principles is essential.

Added Advantage

• A Master's degree (NQF 9 level) in statistics, mathematics, computer science or other quantitative fields.

Required competencies:
(skills, knowledge, and behavioural attributes)

• Ability to use scripting languages such as Bash or Python to automate system tasks and workflows.
• Adept at engaging with researchers, delivering user training, and developing clear, comprehensive technical documentation.
• Adaptable to the rapidly evolving landscape of research IT infrastructure, with a proactive approach to acquiring new skills and technologies.
• A high level of integrity in handling sensitive information
• Ability to work independently as well as part of a team, use initiative, and be flexible.
• Sound knowledge of university research environment, including relevant legislation and policies
• Project management skills
• Excellent communication skills– written and verbal
• Excellent interpersonal skills

In your application, you are encouraged to highlight your strengths and include anything else you deem exceptional and outstanding to be considered by the selection panel. In addition, please attach a cover letter motivating your suitability, a detailed curriculum vitae including contact details of three referees, and your highest qualification to your online profile.

To be considered for this vacancy, you must click on the Apply for this Job link below or apply directly via UWC Careers at For any queries, please contact the Human Resources Department at /9763/9708/3551/3756 or email: e-

DISCLAIMER: By applying for the position, you consent to the University sharing your application, including curriculum vitae, with University stakeholders to process the application. In line with the University's commitment to diversifying its workforce, preference will be given to suitably qualified applicants in line with our Employment Equity Targets. The official retirement age at UWC is 65 years. The University reserves the right to not make an appointment, make an appointment at a different level, seek additional candidates and may conduct competency assessments.

This is a full-time, on-site role for a Clinical Research Associate based in Durban. The Clinical Research Associate will oversee the daily operations of clinical trials, ensure compliance with protocols, and manage research activities. Responsibilities include coordinating with clinical trial sites, monitoring the progress of studies, and maintaining accurate documentation. The role involves close collaboration with other clinical research professionals to ensure the integrity and quality of the research data.

Responsibilities:

• Assume the role of regional monitor for all trials conducted in the VM-CTU for an estimated 5 trials per annum.
• Develop and maintain Standard Operating Procedures relevant to the portfolio.
• Create trial monitoring plans in conjunction with the trial sponsor representatives.
• Conduct study initiation visits for each new trial protocol to assess site readiness for study activation.
• Conduct trial monitoring (clinic, laboratory and pharmacy) to ensure compliance with study protocols, SOPs, ICH-GCP, and local regulatory requirements.
• Review case report forms (CRFs), source documents, and data entry to verify accuracy, completeness, and timeliness.

Qualifications

• A bachelor's degree in a health-related or life sciences discipline (e.g., Pharmacy, Nursing, Medical Sciences, Clinical Research, or equivalent).
• At least 2–3 years of experience monitoring clinical trials with knowledge of clinical trials operations, preferably early-phase (Phase I/II) studies.
• Solid knowledge of SA GCP guidelines, ICH-GCP guidelines, South African Ethics in Health Research Guidelines, SAHPRA and international regulatory requirements.
• Prior experience in monitoring and/or trial coordination, within an academic or as a CRA in industry-sponsored trial setting.
• Strong understanding of investigational product accountability, safety reporting, and protocol compliance.
• Proficiency in MS Office (Word, Excel, PowerPoint, Outlook) and familiarity with electronic data capture (EDC) systems.
• Experience working within a multidisciplinary research environment is an advantage.

Job Type: Permanent

Work Location: In person