24 Informatics Nurse jobs in South Africa

Company Description

We are the company that cares – for our staff, for our clients, for our partners and for the quality of the work we do. A dynamic, global company founded in 1995, we bring together more than 2,700 driven, dedicated and passionate individuals. We work on the frontline of medical science, changing lives, and bringing new medicines to those who need them.

Job Description

You will join a widespread, yet closely-knit team with the same mentality and desire to develop smart and intelligent approach to project monitoring. You will help to shape the future of effective risk-based monitoring at PSI and ensure higher quality of study data. You will spend time monitoring study data remotely, identifying errors and issues with site performance.

Hybrid position after trial period.

You will:

• Review EDC, IxRS, Laboratory and other vendors' data and clinical listings
• Identify single errors and systematic issues related to site performance
• Generate, follow up and resolves data queries and site issues
• Identify and record protocol deviations
• Assist to Central Monitoring Manager with administrative activities, including managing study data, documents and reports
• Ensure site monitors receive information on site related risk & issues. Escalate findings to study teams
• Assists with root cause investigation and follow up on site performance signals identified during central monitoring review

Qualifications

• College/University degree or an equivalent combination of education, training & experience
• Prior experience in Clinical Research
• Experience in central monitoring and clinical data review is a plus
• Full working proficiency in English
• Proficiency in MS Office applications
• Analytical mindset and attention to detail
• Ability to learn, plan and work in a dynamic team environment

Additional Information

Make the right call and take your career to a whole new level. Join the company that focuses on its people and invests in their professional development and success.

Looking for data management expert, who has prior experience in performing scientific (complex) clinical data review in close collaboration with the Study Responsible Physicians (SRP) and Study Responsible Scientists (SRS)

Prior experience of closely collaborating with the SRP, SRS, Data Management functions and the rest of the study team members when implementing the data management related activities for protocols, with focus on more complex indication and therapy related elements of the study.

Has prior experience of being involved and driving discussions with SRP/SRS and collaborates with the Data management team to establish, align, and confirm scientific clinical data review expectations for assigned trial(s).

Extensive prior experience of 4+ years supporting studies within the therapeutic area Oncology or CV&M.

Rave experience mandatory

Deliverables:

• Services rendered will adhere to applicable Client SOPs, WIs, policies, local regulatory requirements, ICH-GCP, etc.
• Provides scientific data review support for more than one low to moderate complexity trial or one high complexity trial.
• The data management expert who, within the therapeutic area, is performing scientific (complex) clinical data review in close collaboration with the Study Responsible Physicians (SRP) and Study Responsible Scientists (SRS). Tapping into technical and clinical expertise, closely collaborating with the SRP, SRS, Data Management functions and the rest of the study team members when implementing the data management related activities for protocols, with focus on more complex indication and therapy related elements of the study. Reviews all necessary data flows, the Data Management Plans and performs continuous (complex) data review activities on the studies in the assigned program.
• Involved in study related activities from the protocol design stage onwards, providing input into the study specific and/or indication specific data collection tools.
• Reviews (complex) scientific study data, manages CDM and SRS/SRP related queries in EDC system. Involvement in other review activities (e.g., Coding, SAE reconciliation) is possible.
• Leads and/or attends meetings as appropriate.
• Takes a leadership role with SRP/SRS and collaborates with the GDM to establish, align and confirm scientific clinical data review expectations for assigned trial(s).
• With the trial customer, CRO and other functional partners in relation to CDM related activities:
• Reviews content and integration requirements for eCRF and other data collection tools
• Establishes conventions and quality expectations for clinical data.
• Set timelines and follow‐up regularly to ensure delivery of all Clinical Data Management milestones
• Creates the Integrated Review Plan ensuring appropriate quality, scientific content, organization, clarity, accuracy, format, and consistency. Reviews related clinical data management documents. Ensures compliance with regulatory guidelines and documentation requirements.
• Ensures real‐time inspection readiness of all assigned deliverables for the trial; participate in Regulatory Agency inspection and Client internal audits as necessary.
• Plans and tracks applicable CDM deliverables. Ensures CDM deliverables are on time.
• Takes a leadership role in collaborating with the SRS/SRP to ensure that DM and Therapeutic Area trial needs and deliverables are met.
• Identifies and communicates lessons learned, best practices and frequently asked questions at the trial level.
• Identifies and participates in process, system, and tool improvement initiatives within clinical data management.
• Therapeutic Area - Oncology, Cardiovascular and Immunology

Education/Experience

• BS/BA degree or higher preferably in Health Sciences, or BS/BA degree or higher with professional clinical experience/exposure.
• 4 years Data management experience. Data Management experience preferably including clinical data review or significant experience with clinical data review. Knowledge in medical terminology would be preferable
• Must have experience in supporting the eCRF build
• Rave knowledge and experience mandatory

This role is not eligible for UK visa sponsorship
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more

Clinical Data Risk Analyst - Sponsor Dedicated

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

Clinical Data Risk Analyst - (Office or Remote working)

South Africa or Bulgaria

The Role:

We are looking for a Clinical Data Risk Analyst to join the Clinical Risk Management team at ICON. Candidates for this exciting opportunity should have strong knowledge of Clinical Research, Risk Based Quality Management, and Central Monitoring in the Pharma or CRO industry.

As functional lead of Clinical Risk Management, the Clinical Data Risk Analyst is responsible for set-up and implementation of Central Monitoring on a portfolio of clinical studies.

The Role:

• Recognize, exemplify and adhere to ICON's values, which center on Collaboration, Agility, Integrity and Inclusion
• Recognize the importance of and create a culture of process improvement with a focus on streamlining our processes adding value to our business and meeting client needs
• Creation and ownership of the Central Monitoring Plan
• Provide input to study risk assessment and propose appropriate and tailored risk indicators for central analysis, in line with holistic data monitoring model.
• Support set-up and testing of data analysis platform
• Review clinical study data and make independent decisions to identify potential site performance and site organization issues.
• Manage operational risk log for Clinical Risk Management activities.
• Train and support the project teams about interpretation of Central Monitoring Signals and relevant decision making for study conduct.
• Support preparation, conduct and follow-up of the Quality Risk Review Meetings for effective communication with the cross functional project team to ensure adequate decisions are taken about the study monitoring strategy and effective resolution of site performance issues.
• Oversee Clinical Risk Management project budget, scope of work, forecasting.
• Communicate effectively with the project team: CRAs, Project Managers, Clinical Trial Managers, DM Staff, Medical staff, Scientific Council to ensure adequate decisions are taken about the study monitoring strategy and effective resolution of site performance issue.
• Support cross functional and external Data Analysis Platform users with system use.
• Act as mentor for Central Monitoring team members.
• Travel (approximately 5%) domestic and/or international.
• Other duties as assigned.

To be successful in the role, you will ideally have:

• University/Bachelor's Degree in medicine, science or equivalent degree/experience
• Thorough knowledge of ICH GCP and relevant regulations for the conduct of clinical trials, with specific focus on updates about Risk Based Quality Management and Central Monitoring
• 3-4 years' experience in Clinical Research (CRA or DM background), or relevant skillset
• Knowledge of database technologies and processes
• Fluent in written and spoken English.
• Excellent communication and interpersonal skills, attention to detail
• Demonstrate ownership and accountability for achieving results.
• Ability to work within a team environment and manage competing priorities in a changeable environment.
• Proven Functional Lead skills and the ability to work independently and apply critical thinking skills to resolve study related issues.
• Due to the nature of this position, it may be required for the employee to travel. Therefore, dependent on the employee's location, the employee may be required to possess a valid Driver's license and passport.

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs
• Competitive retirement planning offerings to maximise savings and plan with confidence for the years ahead
• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others

ICON, including subsidiaries, is an equal opportunity and inclusive employer and is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

Visit our

careers site

to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

As a Junior Clinical Data Manager, you will support the end-to-end delivery of Data Management services for mid-sized or less complex studies. This role offers hand-on experience in study set-up, database validation, and data cleaning, while helping ensure high-quality deliverables are completed on time and meet customer expectations. You will learn to navigate Data Management workflows and contribute to achieving quality and timeline targets in a collaborative, fast-paced environment.

The responsibilities for the Junior Clinical Data Manager include, but are not limited to, the following:

• Take ownership of assigned Data Management tasks with minimal supervision, supporting end-to-end delivery of study activities.
• Assist with study set-up, including database design, validation, and routine data cleaning.
• Support data review processes by generating queries and performing quality checks in accordance with established protocols.
• Manage the coordination of Data Management related activities.
• Lead database design activities by creating data entry screens, system queries, and performing eCRF or system query validation/testing in the EDC database.
• Perform medical coding activities, using standard dictionaries such as MedDRA and WHODrug Global, when applicable.
• Conduct peer-to-peer quality reviews and assist in resolving study-related data discrepancies.
• Ensure timely filing of all study related documentation in the eTMF.
• Contribute to project documentation and participate in sponsor meetings, study team discussions, and audits.
• Mentor junior team members and actively contribute to process improvement initiatives.
• Escalate issues to senior team members while adhering to internal procedures and timlines.

• Excellent communication and interpersonal skills
• Flexibility and multitasking ability
• Problem-solving skills
• Thrive while working under pressure
• A keen eye for detail
• Work independently (and remotely) and is a great team player that solves issues in a collaborative manner
• Flexible approach to work
• Well organized and plan correctly
• Client-focused
• Knowledge of Microsoft Office and the ability to learn about new software and systems
• Focused on delivering high-quality results on time
• Sensitive to cross-cultural differences.

• Bachelor's degree in Life Sciences, Health Sciences, Information Technology, or a related field (or equivalent practical experience).
• 1-2 years of experience in Clinical Data Management or a related role.
• Basic familiarity with clinical trial processes, Data Management Systems, database validation, and quality control practices.

You will join a young, very dynamic, and fast-growing private research organization. Our passionate, truly multicultural, and diverse team of nearly 300 colleagues and nearly 40 nationalities include epidemiologists, clinical operations, CRAs, CTAs, data scientists, statisticians, data analysts, medical writers, safety and pharmacovigilance specialists, project managers and business support professionals spreading over 20 countries.

We all work remotely, setting our own time schedule, based on a "getting the job done" mentality. This has a positive impact in our work-life balance. Our headquarters are in Leuven (Belgium), but we also have local and regional offices located in Rotterdam (the Netherlands), Bogota (Colombia), Johannesburg (South Africa), Bangkok (Thailand), Paris (France), Casablanca (Morocco) and Durham (United States). You may need to travel occasionally.

At P95, we are a collaborative and international team that works on diverse projects, topics, and clients and faces interesting challenges. There is a high level of empowerment, flexibility, autonomy as well as opportunities for research and development, to make things happen. We have an open culture of respect and inclusion. Consequently, we value self-reliance, initiative, and responsibility of everyone in our team to meet our internal and external customers' expectations. Finally, our colleagues experience a strong sense of meaning and purpose driven by the scientific nature and impact of our work.

Visit our website to learn more about who we are and what we do. If you are the one for this job, send your application by filling out the following short form. The call will remain open until the position is filled.

P95 is an Equal Opportunities Employer. The company is committed to equal employment opportunities regardless of age, sexual orientation, gender, pregnancy, religion or belief, union belief, wealth, birth, nationality, ethnic origin, disability, medical history, skin color, marital status, genetic information, parental status, social origin, or condition. We base all our employment decisions on merit, job requirements and business needs.

Apply for this job

P95, an Ampersand portfolio company, is a global provider of clinical and epidemiological services related to vaccines and infectious diseases.

Founded in 2011, we are a leader in sourcing, analyzing, and reporting epidemiological data to assist health agencies and pharmaceutical companies in improving access to safe and effective vaccines.

Headquartered in Belgium, P95 has also offices in Europe, North America, South America, South Africa, and SE Asia.

We are passionate about healthcare and helping our customers with innovative medical research. We share a sense of urgency with our customers to deliver timely, pragmatic and useful insights to improve healthcare.

Our clients are from the pharmaceutical industry, public health institutes, academic institutions, WHO, the European Commission and other governmental organizations and Non-Governmental Organizations (NGOs). Our projects focus mainly on infectious diseases, particularly on vaccines.

Permanent employee, Full-time

• South Africa, Remote

Job Purpose
As a Junior Clinical Data Manager, you will support the end-to-end delivery of Data Management services for mid-sized or less complex studies. This role offers hand-on experience in study set-up, database validation, and data cleaning, while helping ensure high-quality deliverables are completed on time and meet customer expectations. You will learn to navigate Data Management workflows and contribute to achieving quality and timeline targets in a collaborative, fast-paced environment.

Responsibilities
The responsibilities for the
Junior Clinical Data Manager
include, but are not limited to, the following:

• Take ownership of assigned Data Management tasks with minimal supervision, supporting end-to-end delivery of study activities.
• Assist with study set-up, including database design, validation, and routine data cleaning.
• Support data review processes by generating queries and performing quality checks in accordance with established protocols.
• Manage the coordination of Data Management related activities.
• Lead database design activities by creating data entry screens, system queries, and performing eCRF or system query validation/testing in the EDC database.
• Perform medical coding activities, using standard dictionaries such as MedDRA and WHODrug Global, when applicable.
• Conduct peer-to-peer quality reviews and assist in resolving study-related data discrepancies.
• Ensure timely filing of all study related documentation in the eTMF.
• Contribute to project documentation and participate in sponsor meetings, study team discussions, and audits.
• Mentor junior team members and actively contribute to process improvement initiatives.
• Escalate issues to senior team members while adhering to internal procedures and timlines.

Experience - the ideal candidate will have

• Excellent communication and interpersonal skills
• Flexibility and multitasking ability
• Problem-solving skills
• Thrive while working under pressure
• A keen eye for detail
• Work independently (and remotely) and is a great team player that solves issues in a collaborative manner
• Flexible approach to work
• Well organized and plan correctly
• Client-focused
• Knowledge of Microsoft Office and the ability to learn about new software and systems
• Focused on delivering high-quality results on time
• Sensitive to cross-cultural differences.

Experience - You Must Also Have These Skills

• Bachelor's degree in Life Sciences, Health Sciences, Information Technology, or a related field (or equivalent practical experience).
• 1-2 years of experience in Clinical Data Management or a related role.
• Basic familiarity with clinical trial processes, Data Management Systems, database validation, and quality control practices.

Why us?

You will join a young, very dynamic, and fast-growing private research organization. Our passionate, truly multicultural, and diverse team of nearly 300 colleagues and nearly 40 nationalities include epidemiologists, clinical operations, CRAs, CTAs, data scientists, statisticians, data analysts, medical writers, safety and pharmacovigilance specialists, project managers and business support professionals spreading over 20 countries.

We all work remotely, setting our own time schedule, based on a "getting the job done" mentality. This has a positive impact in our work-life balance. Our headquarters are in Leuven (Belgium), but we also have local and regional offices located in Rotterdam (the Netherlands), Bogota (Colombia), Johannesburg (South Africa), Bangkok (Thailand), Paris (France), Casablanca (Morocco) and Durham (United States). You may need to travel occasionally.

At P95, we are a collaborative and international team that works on diverse projects, topics, and clients and faces interesting challenges. There is a high level of empowerment, flexibility, autonomy as well as opportunities for research and development, to make things happen. We have an open culture of respect and inclusion. Consequently, we value self-reliance, initiative, and responsibility of everyone in our team to meet our internal and external customers' expectations. Finally, our colleagues experience a strong sense of meaning and purpose driven by the scientific nature and impact of our work.

Do you want to join us?

Visit our website to learn more about who we are and what we do. If you are the one for this job, send your application by filling out the following short form. The call will remain open until the position is filled.

P95 is an Equal Opportunities Employer. The company is committed to equal employment opportunities regardless of age, sexual orientation, gender, pregnancy, religion or belief, union belief, wealth, birth, nationality, ethnic origin, disability, medical history, skin color, marital status, genetic information, parental status, social origin, or condition. We base all our employment decisions on merit, job requirements and business needs.
Apply for this job

About Us
P95, an Ampersand portfolio company, is a global provider of clinical and epidemiological services related to vaccines and infectious diseases.

Founded in 2011, we are a leader in sourcing, analyzing, and reporting epidemiological data to assist health agencies and pharmaceutical companies in improving access to safe and effective vaccines.

Headquartered in Belgium, P95 has also offices in Europe, North America, South America, South Africa, and SE Asia.

We are passionate about healthcare and helping our customers with innovative medical research. We share a sense of urgency with our customers to deliver timely, pragmatic and useful insights to improve healthcare.

Our clients are from the pharmaceutical industry, public health institutes, academic institutions, WHO, the European Commission and other governmental organizations and Non-Governmental Organizations (NGOs). Our projects focus mainly on infectious diseases, particularly on vaccines.

Apply for this job

We are looking forward to hearing from you

Thank you for your interest in P95. Please fill out the following short form. Should you have difficulties with the upload of your data, please send an email to
-
Data privacy statement

Uploading document. Please wait.

Please add all mandatory information with a * to send your application.

Parexel is currently seeking a Senior Clinical Data Analyst to join us in either South Africa, Poland or the UK, dedicated to a single sponsor.

This role will be responsible for performing Data Management activities that support the sponsor's commercial and development projects worldwide. The successful candidate will participate as an active member of a multi-disciplinary team to plan and execute the Data Management tasks required for phase I – IV studies. The Senior Clinical Data Analyst has a broad, fundamental knowledge of the data management process and can perform most required tasks with minimal guidance.

Working as a Senior Clinical Data Analyst at Parexel FSP offers tremendous long-term job security and prospects. We undertake vital clinical studies for sponsors including the leading global biotechs and Pharma top 50. And we have an incredible pipeline of work.

Expect exciting professional challenges in inspiring studies, but with time for your outside life.

This will be a fully remote home-based position. RAVE experience is strongly preferred.

Responsibilities

• Lead a large clinical study or a series of related studies with minimum guidance.
• Represents Data Management on the CTWG for assigned studies.
• Provide mentoring and training to lower-level Data Management staff assigned to your studies.
• Manage and monitor the progress of data management activities with CROs or other vendors on assigned studies; build effective relationships with CRO / vendor counterparts.
• Review protocols for appropriate data capture including electronic Case Report Form (eCRF) design.
• Be able to perform a thoroughly detailed review of eCRF data requirements.
• Interact with CRAs, programmers, study managers and statisticians in designing eCRFs and creating the annotated eCRF and CRF completion guidelines.
• Lead the development of data edit check specifications and data listings.
• Coordinate the design and testing of Electronic Data Capture (EDC) systems according to company standards. Able to resolve EDC system issues with team members.
• Develop or lead the development of the Data Management Plan for a clinical study.
• Able to review and provide feedback to the clinical team on other study documents e.g. Clinical Monitoring plans, Statistical analysis plans and vendor specifications.
• Provide training on the EDC system and/or eCRF Completion Guidelines at Investigator Meetings and to internal and external study team members as needed.
• Perform reconciliation of header data from external data sources against the clinical database.
• Perform Serious Adverse Event reconciliation activities according to SOPs and guidelines.
• Lead database upgrades/migrations including performing User Acceptance Testing.
• Maintain study workbooks and data management files.
• Perform database lock and freeze activities per company SOPs.
• Participate in regular team meetings and provide input when appropriate.
• Provide input into the development of data management SOPs, Work Instructions, and process documents; take a leadership role in the development of assigned documents.
• Contribute to a professional working environment including the application of the sponsor's Code of Business Conduct and Ethics.
• Assist with the training of new employees and/or contractors.

Here are a few requirements specific to this advertised role.

• Bachelor's Degree required, preferably in the scientific/healthcare field.
• Good project management skills and a proven ability to multitask.
• At least five years' experience in Data Management for the pharmaceutical/biotechnology industry.
• Understanding of the scope and focus of Phase I – IV clinical studies, and a proven ability to perform some of the core Data Management tasks and interact with vendors.
• A comprehensive understanding of regulatory guidelines and industry standards (e.g., ICH/FDA guidance, CDISC standards, GCDMP, 21 CFR 11, MedDRA, WHO Drug Dictionaries, etc.) and their application to Data Management practice.
• Attention to detail and the ability to work individually, within a multi-disciplinary team, as well as with external partners and vendors.
• Strong English language written and verbal communication skills.
• Able to travel to meetings or training seminars on occasion.
• Possesses solid computer system and technical skills with a strong ability to learn multiple computer applications. Prior experience with different Data Management systems and technologies, and Electronic Data Capture systems is desirable.
• Experience and understanding of the Oncology or CNS therapeutic area and with Phase III pivotal studies are desirable.

We care about our people and your passion, as they are the key to our success, and provide an open and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. In addition, you will have the opportunity to develop within your role and tackle further responsibilities or develop your skill set within other related departments of Parexel.

Who Are Parexel
Parexel supports clinical studies across the full range of therapeutic areas, and we have longstanding partnerships with a vast client base.

We supported the trials of most of today's top 50 best-selling drugs, but equally we enable more niche drug developments that are critical to the well-being of many patients.

You'll be an influential member of the wider team.

Not quite the role for you?
Join Our Talent Community and we'll reach out with job alerts when positions that match your career interests become available. We'll also share periodic updates about the latest company news and events.

Sign up today

Junior Clinical Data Coordinator

At Mango5, we believe in empowering people through innovation, precision, and care. We support global clinical research by ensuring that data is managed with accuracy, integrity, and speed — helping bring better treatments to market faster. As part of our team, you’ll play a vital role in ensuring the quality and reliability of clinical trial data while building a career in a growing, specialized field.

Key Responsibilities

• Manage incoming clinical research data across multiple worksheets, systems, and image files.


• Ensure accurate data entry and escalate issues appropriately.


• Apply critical thinking and discretion, particularly in relation to adverse events.


• Upload visit data within defined timelines.


• Review project data and deliver results to stakeholders promptly.


• Request and manage source data corrections as required.


• Enter/upload data into third-party platforms (e.g., EDC systems).


• Review and resolve data queries.


• Participate in database lock activities.


• Conduct regular quality checks of data for completeness, accuracy, and integrity (ALCOA+).


• Assist in the identification and reporting of potential adverse events.


• Maintain project documentation and the Trial Master File (TMF).


• Assist in the creation and maintenance of case report forms.

Qualifications:

• Matric certificate (minimum requirement).


• Bachelor’s degree in a life sciences-related field (Advantagouss).


• 1–2 years of clinical trial and data management experience.


• Knowledge of Good Clinical Practices (GCP).


• Experience with electronic data capture (EDC) systems (preferred).


• Strong skills in the use of technology, tools, operating systems, and software.


• Strong organizational skills with experience balancing priorities and resources.


• Strong attention to detail.


• Critical thinking and problem-solving skills.


• Ability to plan proactively, anticipate challenges, and operationalize solutions.


• Able to work thoughtfully and decisively, fostering an inclusive work environment.


• Clear criminal record.


• Clear credit record.

Working hours:

• 45-Hour work week with rotating shifts between 16:00 - 4:00 (Daylight savings)


• Rotating working days from Monday to Sunday to ensure consistent global support


• Dynamic holidays

Remuneration

• Basic salary: Market-Related


• Shift allowance


• Commission

Benefits

• Medical Insurance (after 3 months of employment)


• Access to our LMS Portal for continuous learning and development


• Emergency Assistance

If you meet the criteria but do not hear from us within two weeks, your profile will be kept on file for future opportunities.

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

Senior Clinical Data Science Lead (Advanced Clinical Data Manager)
Sponsor Dedicated
South Africa
We are currently seeking a Senior Clinical Data Science Lead to join our diverse and dynamic team. As a Senior Clinical Data Science Lead at ICON, you will play a pivotal role in leading the analysis, interpretation, and management of clinical data to drive the success of our clinical trials. You will contribute to the advancement of innovative treatments and therapies by overseeing data science initiatives and ensuring data quality and integrity across studies.

What You Will Be Doing

• Leading the development and implementation of clinical data management strategies to optimize data collection, analysis, and reporting.
• Collaborating with cross-functional teams to ensure the accurate integration of data science techniques into clinical trial designs.
• Overseeing the analysis of clinical data to provide actionable insights that inform study decisions and outcomes.
• Providing strategic guidance on data governance, quality control, and compliance with regulatory requirements.
• Establishing partnerships with key stakeholders to leverage the latest advancements in data science and technology in clinical research.

Your Profile

• Advanced degree in a relevant field such as data science, biostatistics, or life sciences.
• Extensive experience in clinical data science, with a strong focus on data management and analysis in clinical trials.
• Strong leadership skills and a proven ability to manage cross-functional teams in a fast-paced, matrix environment.
• Expertise in data analysis tools, statistical software, and data visualization techniques.
• Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive change in a complex organization.

What ICON Can Offer You
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our Benefits Examples Include

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply

Senior Clinical Data Science Lead (Sponsor Dedicated)

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

Senior Clinical Data Science Lead (Advanced Clinical Data Manager)

Sponsor Dedicated

South Africa

We are currently seeking a Senior Clinical Data Science Lead to join our diverse and dynamic team. As a Senior Clinical Data Science Lead at ICON, you will play a pivotal role in leading the analysis, interpretation, and management of clinical data to drive the success of our clinical trials. You will contribute to the advancement of innovative treatments and therapies by overseeing data science initiatives and ensuring data quality and integrity across studies.

What You Will Be Doing:

• Leading the development and implementation of clinical data management strategies to optimize data collection, analysis, and reporting.
• Collaborating with cross-functional teams to ensure the accurate integration of data science techniques into clinical trial designs.
• Overseeing the analysis of clinical data to provide actionable insights that inform study decisions and outcomes.
• Providing strategic guidance on data governance, quality control, and compliance with regulatory requirements.
• Establishing partnerships with key stakeholders to leverage the latest advancements in data science and technology in clinical research.

Your Profile:

• Advanced degree in a relevant field such as data science, biostatistics, or life sciences.
• Extensive experience in clinical data science, with a strong focus on data management and analysis in clinical trials.
• Strong leadership skills and a proven ability to manage cross-functional teams in a fast-paced, matrix environment.
• Expertise in data analysis tools, statistical software, and data visualization techniques.
• Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive change in a complex organization.

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

Visit our

careers site

to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.