57 Clinical Research Associate jobs in South Africa

Job Summary

Our clinical activities are growing rapidly, and we are currently seeking full-time, home-based Clinical Research Associates to join our Clinical Monitoring team in South Africa. This position will work with a team to accomplish tasks and projects that are instrumental to the company’s success. The Clinical Research Associate at Medpace is offered the unique opportunity to be involved at every stage of the drug development process by providing unrivalled support to our customers. If you want an exciting career where you use your medical or health background and education, travel extensively and are instrumental in the clinical trials process, this could be the opportunity for you.

We kindly ask to submit applications in English.

Entry level associates with research associate or trial assistant-type backgrounds may also be considered.

Responsibilities

• Conduct pre-study, initiation, monitoring, and closeout visits for research sites;
• Perform source document verification and case report form review;
• Perform regulatory document review;
• Conduct study drug inventory;
• Perform adverse event and serious adverse event reporting and follow-up;
• Assess patient recruitment and retention.

Qualifications

• Minimum a Bachelor of science in health-related field or equivalent
• Minimum of 1-year independent clinical monitoring; Entry level associates may be considered with relevant trial assistant or research associate-type backgrounds
• Broad knowledge of medical terminology and clinical patient management
• Basic knowledge of drug therapy techniques and clinical research methodologies
• Comprehensive knowledge of Local Regulations and ICH GCP
• Excellent oral and written communication skills
• Fluency in English
• Great attention to detail
• Must hold a valid driver’s license

Medpace Overview

Medpace is a full-service clinical contract research organization (CRO). We provide Phase I-IV clinical development services to the biotechnology, pharmaceutical and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through its scientific and disciplined approach. We leverage local regulatory and therapeutic expertise across all major areas including oncology, cardiology, metabolic disease, endocrinology, central nervous system, anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, employing more than 5,000 people across 40+ countries.

Why Medpace?

People. Purpose. Passion. Make a Difference Tomorrow. Join Us Today.

The work we’ve done over the past 30+ years has positively impacted the lives of countless patients and families who face hundreds of diseases across all key therapeutic areas. The work we do today will improve the lives of people living with illness and disease in the future.

Medpace Perks

• Flexible work environment
• Competitive compensation and benefits package
• Competitive PTO packages
• Structured career paths with opportunities for professional growth
• Company-sponsored employee appreciation events
• Employee health and wellness initiatives

Awards

• Recognized by Forbes as one of America's Most Successful Midsize Companies in 2021, 2022, 2023 and 2024
• Continually recognized with CRO Leadership Awards from Life Science Leader magazine based on expertise, quality, capabilities, reliability, and compatibility

What to Expect Next

A Medpace team member will review your qualifications and, if interested, you will be contacted with details for next steps.

EO/AA Employer M/F/Disability/Vets

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Job Overview
Perform monitoring and site management work for a variety of protocols, site and therapeutic areas.

Essential Functions
• Perform site monitoring visits (selection, initiation, monitoring and close-out visits) in accordance with contracted scope of work and regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines.
• Work with sites to adapt, drive and track subject recruitment plan in line with project needs to enhance predictability.
• Administer protocol and related study training to assigned sites and establish regular lines of communication with sites to manage ongoing project expectations and issues.
• Evaluate the quality and integrity of study site practices related to the proper conduct of the protocol and adherence to applicable regulations. Escalate quality issues as appropriate.
• Manage the progress of assigned studies by tracking regulatory submissions and approvals, recruitment and enrollment, case report form (CRF) completion and submission, and data query generation and resolution. May support start-up phase.
• Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP / ICH and local regulatory requirements.
• Create and maintain appropriate documentation regarding site management, monitoring visit findings and action plans by submitting regular visit reports, generating follow-up letters and other required study documentation.
• Act as a mentor for clinical staff including conducting co-monitoring and training visits.
• Collaborate and liaise with study team members for project execution support as appropriate.
• If applicable, may be accountable for supporting development of project subject recruitment plan on a per site basis.
• If applicable, may be accountable for site financial management according to executed clinical trial agreement and retrieve invoices according to local requirement.

Qualifications
• Bachelor's Degree Degree in scientific discipline or health care preferred. Req
• Requires at least 3 years of year of on-site monitoring experience.
• Equivalent combination of education, training and experience may be accepted in lieu of degree.
• In depth knowledge of, and skill in applying, applicable clinical research regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines.
• Strong therapeutic and protocol knowledge as provided in company training.
• Computer skills including proficiency in use of Microsoft Word, Excel and PowerPoint and use of a laptop computer and iPhone and iPad (where applicable).
• Written and verbal communication skills including good command of English language.
• Organizational and problem-solving skills.
• Effective time and financial management skills.
• Ability to establish and maintain effective working relationships with coworkers, managers, and clients.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide . Learn more at

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Job title : Senior Clinical Research Associate, Cape Town based

Job Location : Western Cape, Cape Town Deadline : September 01, 2025 Quick Recommended Links

• Jobs by Location
• Job by industries

StartFragment

Job Description

Job Overview

Perform monitoring and site management work for a variety of protocols, site and therapeutic areas.

Essential Functions

Perform site monitoring visits (selection, initiation, monitoring and close-out visits) in accordance with contracted scope of work and regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines.

Work with sites to adapt, drive and track subject recruitment plan in line with project needs to enhance predictability.

Administer protocol and related study training to assigned sites and establish regular lines of communication with sites to manage ongoing project expectations and issues.

Evaluate the quality and integrity of study site practices related to the proper conduct of the protocol and adherence to applicable regulations. Escalate quality issues as appropriate.

Manage the progress of assigned studies by tracking regulatory submissions and approvals, recruitment and enrollment, case report form (CRF) completion and submission, and data query generation and resolution. May support start-up phase.

Ensure copies / originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP / ICH and local regulatory requirements.

Create and maintain appropriate documentation regarding site management, monitoring visit findings and action plans by submitting regular visit reports, generating follow-up letters and other required study documentation.

Act as a mentor for clinical staff including conducting co-monitoring and training visits.

Collaborate and liaise with study team members for project execution support as appropriate.

If applicable, may be accountable for supporting development of project subject recruitment plan on a per site basis.

If applicable, may be accountable for site financial management according to executed clinical trial agreement and retrieve invoices according to local requirement.

Qualifications

Bachelor's Degree in scientific discipline or health care preferred. Req

Requires at least 3 years of year of on-site monitoring experience.

Equivalent combination of education, training and experience may be accepted in lieu of degree.

In depth knowledge of, and skill in applying, applicable clinical research regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines.

Strong therapeutic and protocol knowledge as provided in company training.

Computer skills including proficiency in use of Microsoft Word, Excel and PowerPoint and use of a laptop computer and iPhone and iPad (where applicable).

Written and verbal communication skills including good command of English language.

Organizational and problem-solving skills.

Effective time and financial management skills.

Ability to establish and maintain effective working relationships with coworkers, managers, and clients.

EndFragment

Medical / Healthcare jobs

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Job Overview
Perform monitoring and site management work for a variety of protocols, site and therapeutic areas.
Essential Functions
- Perform site monitoring visits (selection, initiation, monitoring and close-out visits) in accordance with contracted scope of work and regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines.
- Work with sites to adapt, drive and track subject recruitment plan in line with project needs to enhance predictability.
- Administer protocol and related study training to assigned sites and establish regular lines of communication with sites to manage ongoing project expectations and issues.
- Evaluate the quality and integrity of study site practices related to the proper conduct of the protocol and adherence to applicable regulations. Escalate quality issues as appropriate.
- Manage the progress of assigned studies by tracking regulatory submissions and approvals, recruitment and enrollment, case report form (CRF) completion and submission, and data query generation and resolution. May support start-up phase.
- Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP / ICH and local regulatory requirements.
- Create and maintain appropriate documentation regarding site management, monitoring visit findings and action plans by submitting regular visit reports, generating follow-up letters and other required study documentation.
- Act as a mentor for clinical staff including conducting co-monitoring and training visits.
- Collaborate and liaise with study team members for project execution support as appropriate.
- If applicable, may be accountable for supporting development of project subject recruitment plan on a per site basis.
- If applicable, may be accountable for site financial management according to executed clinical trial agreement and retrieve invoices according to local requirement.
Qualifications
- Bachelor's Degree Degree in scientific discipline or health care preferred. Req
- Requires at least 3 years of year of on-site monitoring experience.
- Equivalent combination of education, training and experience may be accepted in lieu of degree.
- In depth knowledge of, and skill in applying, applicable clinical research regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines.
- Strong therapeutic and protocol knowledge as provided in company training.
- Computer skills including proficiency in use of Microsoft Word, Excel and PowerPoint and use of a laptop computer and iPhone and iPad (where applicable).
- Written and verbal communication skills including good command of English language.
- Organizational and problem-solving skills.
- Effective time and financial management skills.
- Ability to establish and maintain effective working relationships with coworkers, managers, and clients.
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create connections that accelerate the development and commercialization of innovative medical treatments. Everything we do is part of a journey to improve patient outcomes and population health worldwide.
To get there, we seek out diverse talent with curious minds and a relentless commitment to innovation and impact. No matter your role, everyone at IQVIA contributes to our shared goal of helping customers improve the lives of patients everywhere. Thank you for your interest in growing your career with us.
EEO Minorities/Females/Protected Veterans/Disabled

Job Family

Risk, Audit and Compliance

Regulatory Compliance

Manage Self: Professional

Job Purpose

• To consult, advise and report to the Group regarding relevant domestic and international legislation; compliance and governance to ensure adherence to relevant codes; regulations and rules thereby minimising risk to and protecting the reputation of Nedbank.

Job Responsibilities

• Advise business on best practice for regulatory compliance by ensuring the business is educated on the regulatory landscape and by creating awareness around compliance implication of daily duties.
• Understanding, positioning and articulating for legislative change.
• Support the central function by assisting in developing of policies, procedures, frameworks and tools with specific focus on relevant risk legislation, for the benefit of the larger organisation.
• Define governance frameworks and ensure good governance practice.
• Advise and support the Group to ensure regulatory compliance standards are met and risks are mitigated.
• Identify, define and agree on the regulatory universe applicable for each relevant Business Unit, mitigating risks.
• Provide regulatory support and expertise in the formulation and completion of compliance risk management plans (CRMP's).
• Advise and support business in terms of applicability of legislation and in so doing, mitigate risk.
• Ensure that compliance risk as well as all other impacted risks are adequately identified and in so doing, guide the business in terms of addressing such risk.
• Guide business to ensure that business policies contain the right content addressing legislative requirements thereby working toward an effective and adequate control environment
• Advise business of changes in legislation and identify potential impact of these changes on the business.
• Influence the enhancement of business processes and methodologies specific to the area.
• Support and empower the Group to prevent compliance breaches and reputational risk from occurring, which could result in financial penalties.
• Create and strengthen awareness of the business compliance risk management in relation to evolving regulatory landscape.
• Promote and facilitate cross Cluster engagement, manage and improve business efficiencies.
• Engage with stakeholders on findings of compliance risk and control assessments to ensure action plans adhere to regulatory standards.
• Enable management to make informed decisions and prevent compliance breaches.
• Ensure that stakeholder relationships are effectively managed.
• Obtain buy-in for developing new and/or enhanced processes that will improve the functioning of stakeholders' businesses.
• Stay abreast of developments in field of expertise, ensuring personal and professional growth.
• Understand and embrace the Nedbank vision and values, leading by example.
• Manage performance through training, development and addressing poor performance through relevant channels.
• Educate self-regarding business, through engagement, meetings, procedures and policy awareness.
• Contribute to a culture of transformation by participating in Nedbank culture building initiatives, business strategy, and CSI.

Essential Qualifications - NQF Level

• LLB

Essential Certifications

• Compliance Practitioner (SA) / CPrac (SA) / Admitted Attorney

Type of Exposure

• Relevant regulatory and compliance experience in relation to the following areas – inter alia Banks Act, Financial Intelligence Centre Act, National Credit Act,
• Managed risk and compliance
• Interpretation of legislation
• Checking accuracy of business feedback in response to evolving regulatory landscape
• Regulatory Reporting

Minimum Experience Level

• 5-10 years in a Compliance/ Legal/ Governance role

Technical / Professional Knowledge

• Relevant Governance controls and regulatory knowledge
• Corporate Governance and Compliance
• Compliance reporting
• Policy and Procedural Knowledge
• Building Trusting Relationships
• Managing Work
• Quality Orientation
• Stress Tolerance

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Please contact the Nedbank Recruiting Team at +27 860 555 566

If you can't find the job you're looking for, activate job alerts to be one of the first to know when new positions open up.

Nedbank Ltd Reg No 1951/0009/06.
Authorised financial services and registered credit provider (NCRCP16).

For assistance please contact the Nedbank Recruiting Team at +27 860 555 566

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Requisition Details & Talent Acquisition Consultant

REQ 138402 - Michelle Thabethe

Location: Sandton

Closing Date: 18 March 2025

Job Family: Risk, Audit and Compliance

Career Stream: Regulatory Compliance

Leadership Pipeline: Manage Self: Professional

Job Purpose

To consult, advise and report to the Group regarding relevant domestic and international legislation; compliance and governance to ensure adherence to relevant codes; regulations and rules thereby minimising risk to and protecting the reputation of Nedbank.

Job Responsibilities

• Advise business on best practice for regulatory compliance by ensuring the business is educated on the regulatory landscape and by creating awareness around compliance implication of daily duties.
• Understanding, positioning and articulating for legislative change.
• Support the central function by assisting in developing of policies, procedures, frameworks and tools with specific focus on relevant risk legislation, for the benefit of the larger organisation.
• Define governance frameworks and ensure good governance practice.
• Advise and support the Group to ensure regulatory compliance standards are met and risks are mitigated.
• Identify, define and agree on the regulatory universe applicable for each relevant Business Unit, mitigating risks.
• Provide regulatory support and expertise in the formulation and completion of compliance risk management plans (CRMP's).
• Advise and support business in terms of applicability of legislation and in so doing, mitigate risk.
• Ensure that compliance risk as well as all other impacted risks are adequately identified and in so doing, guide the business in terms of addressing such risk.
• Guide business to ensure that business policies contain the right content addressing legislative requirements thereby working toward an effective and adequate control environment.
• Advise business of changes in legislation and identify potential impact of these changes on the business.
• Influence the enhancement of business processes and methodologies specific to the area.
• Support and empower the Group to prevent compliance breaches and reputational risk from occurring, which could result in financial penalties.
• Create and strengthen awareness of the business compliance risk management in relation to evolving regulatory landscape.
• Promote and facilitate cross Cluster engagement, manage and improve business efficiencies.
• Engage with stakeholders on findings of compliance risk and control assessments to ensure action plans adhere to regulatory standards.
• Enable management to make informed decisions and prevent compliance breaches.
• Ensure that stakeholder relationships are effectively managed.
• Obtain buy-in for developing new and/or enhanced processes that will improve the functioning of stakeholders' businesses.
• Stay abreast of developments in field of expertise, ensuring personal and professional growth.
• Understand and embrace the Nedbank vision and values, leading by example.
• Manage performance through training, development and addressing poor performance through relevant channels.
• Educate self-regarding business, through engagement, meetings, procedures and policy awareness.
• Contribute to a culture of transformation by participating in Nedbank culture building initiatives, business strategy, and CSI.

Essential Qualifications - NQF Level

• LLB

Essential Certifications

• Compliance Practitioner (SA) / CPrac (SA) / Admitted Attorney

Type of Exposure

• Relevant regulatory and compliance experience in relation to the following areas – inter alia Banks Act, Financial Intelligence Centre Act, National Credit Act.
• Managed risk and compliance.
• Interpretation of legislation.
• Checking accuracy of business feedback in response to evolving regulatory landscape.
• Regulatory Reporting.
• Industry engagements.

Minimum Experience Level

• 5-10 years in a Compliance/ Legal/ Governance role.

Technical / Professional Knowledge

• Relevant Governance controls and regulatory knowledge.
• Corporate Governance and Compliance.
• Compliance reporting.
• Policy and Procedural Knowledge.

Behavioural Competencies

• 360° Decision Making.
• Influencing.
• Building Trusting Relationships.
• Managing Work.
• Quality Orientation.
• Stress Tolerance.

Please contact the Nedbank Recruiting Team at +27 860 555 566

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Senior Regulatory Compliance Manager

A position has become available for a Senior Regulatory Compliance Manager based in Durban.

Job Purpose

Provide advice, guidance, recommendations on the adherence of regulatory compliance practices in client facing divisions ensuring compliance regulatory risks are identified, assessed, and reported on for the Group.

Job Responsibilities

1. Identify and manage all Regulatory requirements of the Group.
2. Manage the completion of all commentary and/or impact assessments requests from various Regulatory Bodies including the Prudential Authority, Financial Intelligence Centre, National Credit Regulator, and Information Regulator.
3. Provide expert guidance and recommendations to ensure adherence to multiple laws and regulations regulating the affairs of the Group.
4. Demonstrate in-depth understanding of key legislation such as the NCA, FAIS Act, POPIA, FIC, and other applicable laws (including subordinate legislation) that impact the Group.
5. Conduct compliance regulatory training, keeping Compliance and all internal stakeholders (1st line) informed and updated on regulatory changes and policy requirements.
6. Build and maintain trusted relationships with internal stakeholders by establishing effective partnerships to identify and manage compliance regulatory risks.
7. Develop and maintain a clear understanding of the scope and nature of the business conducted by 1st line (business acumen).
8. Develop a solid understanding of all high-risk legislation that applies to the Group.
9. Keep abreast of all regulatory developments/changes that may potentially impact the Group and engage with all relevant stakeholders on a timely basis to ensure business readiness and ongoing compliance risk management.
10. Contribute to the creation of a compliance culture and compliance awareness in the division by becoming a trusted advisor.
11. Execute on all Regulatory Compliance projects (end-to-end) within set timelines.
12. Provide advice, guidance, and recommendations on whether regulatory compliance requirements are met.
13. Ensure accurate and timely reporting on any non-compliance, the management of compliance risks, and the state of compliance in the division.
14. Provide advice, guidance, and recommendations to stakeholders on the state of regulatory compliance by reporting on how key risks are being managed, highlighting areas that require immediate attention, and recommending corrective action to stakeholders.
15. Present potential compliance regulatory findings to stakeholders through formal engagement. Take an active part in all Regulatory Compliance governance.
16. Assist in filing regulatory reports to the respective regulators, keeping the Group in good standing with regulatory bodies.

Qualifications:

• LLB Degree
• Admitted Attorney
• Member of the Compliance Institute of SA
• RE5 Accredited: Advantageous
• 5-7 years’ experience in a regulatory compliance position, 3 of which must have been in a managerial role - preferably in financial services.

Salary market related for a senior position.

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Job Description

Responsibilities:

1. Identify and manage all Regulatory requirements of the Group, including mortgage providers and insurance companies offering credit life and homeowners.
2. Manage the completion of all commentary and/or impact assessments requested from various Regulatory Bodies including the Prudential Authority, Financial Intelligence Centre, National Credit Regulator, and Information Regulator.
3. Provide expert guidance and recommendations to ensure adherence to multiple laws and regulations regulating the affairs of the Group.
4. Demonstrate an in-depth understanding of key legislations such as the NCA, FAIS Act, POPIA, FIC, and other applicable laws (including subordinate legislation) that impact the Group.
5. Conduct compliance regulatory training, keeping Compliance and all internal stakeholders (1st line) informed and updated on regulatory changes and policy requirements.
6. Build and maintain trusted relationships with internal stakeholders (i.e., the Division’s 1st line as well as 2nd line functions) by establishing effective partnerships to identify and manage compliance regulatory risks.
7. Develop and maintain a clear understanding of the scope and nature of the business conducted by 1st line (business acumen).
8. Develop a solid understanding of all high-risk legislation that applies to the Group.
9. Keep abreast of all regulatory developments/changes that may potentially impact the Group and engage with all relevant stakeholders on a timely basis to ensure business readiness and ongoing compliance risk management.
10. Contribute to the creation of a compliance culture and compliance awareness in the division by becoming a trusted advisor to 1st line (whilst maintaining independence of mind as part of 2nd line).
11. Execute on all Regulatory Compliance projects (end-to-end) within set timelines.
12. Provide advice, guidance, and recommendations to 1st and 2nd line on whether regulatory compliance requirements are met.
13. Ensure accurate and timely reporting on any non-compliance, the management of compliance risks, and the state of compliance in the division (1st line).
14. Provide advice, guidance, and recommendations to stakeholders on the state of regulatory compliance by reporting on how key risks are being managed, highlighting areas that require immediate attention, and recommending corrective action to stakeholders.
15. Present potential compliance regulatory findings to stakeholders through formal engagement. Take an active part in all Regulatory Compliance governance.
16. Assist in filing regulatory reports to the respective regulators, keeping the Group in good standing with regulatory bodies.

Candidate Requirements

- LLB Degree

- Admitted Attorney

- Member of the Compliance Institute of SA

- RE5

How to Apply

Please forward your CV to . Should you not be contacted within 2 weeks, kindly consider your application unsuccessful.

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Senior Manager Regulatory Compliance

Location: Durban

Well-established financial services client is looking for a Senior Regulatory Compliance Manager with 5 years in a similar position.

Salary: Negotiable based on experience and qualifications

Minimum Requirements:

1. LLB Degree
2. Admitted Attorney
3. Member of the Compliance Institute of SA
4. RE5 Accredited: Advantageous
5. 5 years’ experience in a regulatory compliance position
6. 3 years managerial experience
7. Must come from the financial services industry

Full job description will be discussed in the interview process.

Please apply online.

FROGG Recruitment

We offer:

• Medical Aid Contribution
• Provident Fund Contribution

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