14 Clinical Affairs jobs in South Africa

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function
Medical Affairs Group

Job Sub Function
Medical Science Liaison

Job Category
Scientific/Technology

All Job Posting Locations:
Cleveland, Ohio, United States, Florida (Any City), Irvine, California, United States of America, Maryland (Any City), New Jersey (Any City), North Carolina (Any City), Ohio (Any City), South Carolina (Any City), Washington (Any City)

Job Description
We are searching for the best talent to join our Vision team as a
Principal Medical Science Liaison.
This is a field-based role available in multiple states and cities within the Northeast and Southeast. While specific cities are listed in the Locations section for reference, please note that they are examples only and do not limit your application.

Fueled by innovation at the intersection of biology and technology, we're developing the next generation of smarter, less invasive, more personalized treatments.

Are you passionate about improving and expanding on the possibilities of vision treatments? Ready to join a team that's reimagining how vision is improved? Our Vision team solves the toughest health challenges. Help combine cutting-edge insights, science, technology, and people to encourage eye care professionals and patients to proactively protect, correct and enhance healthy sight for life. Our products and services address these needs – from the pediatric to aging eye – in a patient's lifetime.

Your unique talents will help patients on their journey to wellness. Learn more at

Purpose:
The Medical Science Liaison (MSL) is a field-based member of the Johnson and Johnson Vision (JJV) Medical Affairs team. They provide a strategic connection between our external customers (Key Opinion Leaders and Eye Care Professionals) and internal stakeholders. They are accountable for delivering medical, scientific, and technical information and insights, and initiating & maintaining relationships, internally and externally, to increase awareness of JJV's products and relevant disease states

You Will

• Maintain advanced clinical knowledge of new and growing relevant eye health disease states, advancements in science and evidence in relevant categories.
• Provide medical, scientific, and technical information to relevant customers.
• Initiate and maintain relationships to increase awareness of JJV's products and disease states by designing, developing, and delivering effective presentations and by coordinating symposia and continuing education seminars.
• Collect and follow up on unsolicited medical information requests and assisting in the developing novel clinical study ideas.
• Develop and provide clinical information to current and potential key opinion leaders. Coordinate continuing educational workshops, seminars and programs for relevant health care workers, physicians, and scientists.
• Provide analysis of clinical studies to verify information integrity of the company's products.
• Assist with preparation of product presentations for demonstration to thought leaders, medical groups, government agencies and health systems.
• Coordinate policies and procedures for development and provision of medical and technical information relating to the company's products for use by customers.
• Deliver medical information to internal/external health sources as directed.
• Assist in creation of educational, promotional, and reporting materials for use within the company's departments.
• Ethically gather scientific, customer, and market information on prelaunch and marketed products as directed.
• Demonstrate Johnson & Johnson Credo values and a role model of health care compliance, including HIPPA and privacy.

Qualifications

• Minimum educational requirement: Master's degree or an advanced scientific degree (e.g., OD, PhD, MD, DO highly preferred).
• Minimum of 5 years clinical work experience in field of Optometry/Ophthalmology, and a minimum of 3 years' experience in a customer facing role
• Knowledge of eye diseases and ocular health landscape
• Ability to communicate effectively and build strong partnerships is required
• Demonstrate entrepreneurial spirit and take the initiative, and persevere to overcome challenges
• Excellent presentation skills and strong verbal and written communication skills
• Strong influencing skills to represent needs of stakeholders
• Must be able to prioritize tasks and work effectively in a constantly changing environment
• Strong judgment and balanced decision-making
• Proficient in Microsoft Office Suite (Word, PowerPoint, and Excel) and associated hardware
• Expected Travel 75% or greater

Preferred Qualifications

• Proven track record of people and project management
• Experience in a customer-facing role (Medical Device or Pharma)
• Working knowledge of the Healthcare System and of research procedures
• Experience in understanding the design and execution clinical trials, in particular in the post-market phase
• Experience in creating and delivering scientific presentations, basic experience in medical writing and a general knowledge of biostatistics
• Knowledge of product development, clinical trial design, regulatory requirements, payer landscape, and life cycle management
• Proven ability and experience to develop and foster peer-to-peer, credible relationships with Medical Experts/decision makers
• Experience in adverse event management

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-) or contact AskGS to be directed to your accommodation resource.
The anticipated base pay range for this position is :
$115,000-$195,000

Additional Description For Pay Transparency
Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation –120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year Holiday pay, including Floating Holidays –13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave – 10 days Volunteer Leave – 4 days Military Spouse Time-Off – 80 hours Additional information can be found through the link below.

The Research Professional Nurse functions under the supervision of the Study Coordinator to assist in the maintenance of the integrity of the study goals through the recruitment and care of the clinical trial participants, collection of specimens and data.

• 4-year Degree / Diploma in Nursing
• At least one to two years' experience working in the clinical and/or research sector
• Interpersonal skills
• Decision making and problem-solving skills
• Good record keeping skills
• Fluency in English and isiZulu/Afrikaans/Xhosa
• Good Communication skills
• Familiarity with the Pretoria region
• Working knowledge of Good Clinical Practice (GCP) and the Protection of Human Participants in Research (HSP)
• Professional registration or license requirements Registration with the South African Nursing Council (SANC)
• Participant Recruitment and Consenting / Assenting
• Participant Management
• Data Collection
• Phlebotomy and management of drip lounge patients (putting up drips and monitoring patients)

Clinical Research Associate - Johannesburg

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative treatments and therapies.

What you will be doing

• Conducting site qualification, initiation, monitoring, and close-out visits for clinical trials.

• Ensuring protocol compliance, data integrity, and patient safety throughout the trial process.

• Collaborating with investigators and site staff to facilitate smooth study conduct.

• Performing data review and resolution of queries to maintain high-quality clinical data.

• Contributing to the preparation and review of study documentation, including protocols and clinical study reports

Your profile

• Bachelor's degree in a scientific or healthcare-related field.

• Minimum of 2 years of experience as a Clinical Research Associate.

• In-depth knowledge of clinical trial processes, regulations, and ICH-GCP guidelines.

• Strong organizational and communication skills, with attention to detail.

• Ability to work independently and collaboratively in a fast-paced environment.

• Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver's license

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

Visit our

careers site

to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Job Title: Clinical Research Associate (CRA)

Location: Cape Town, South Africa

Company: ICON Strategic Solutions – FSP

As a Clinical Research Associate, Your Primary Focus Will Be On The End-to-end Management Of Clinical Trials At Assigned Study Sites. You Will

• Collaborate closely with the local study team to meet study goals, timelines, and site commitments.
• Serve as the primary point of contact for study sites, overseeing the preparation, initiation, monitoring, and closure of clinical trials.
• Ensure compliance with international guidelines (ICH-GCP) and local regulations to guarantee the integrity and safety of the study.
• Proactively identify and resolve study-related issues, escalating as necessary to ensure smooth site performance.
• Conduct monitoring visits (both on-site and remote) and manage essential study documentation.
• Assist in site training, patient recruitment, data management, and quality control to ensure the study runs efficiently.
• Maintain accurate and up-to-date records in CTMS and ensure study sites remain inspection-ready at all times.

We're Searching For a Highly Motivated Individual With

• A minimum of 3 years of experience as a CRA or in a similar role, preferably across multiple therapeutic areas.CV and Respiratory are an advantage.
• University degree in Health Science, or a related field.
• To be based in Cape Town.
• Compliance Knowledge: Strong knowledge of ICH-GCP guidelines and local regulatory requirements.
• Communication Skills: Excellent interpersonal and communication skills, with the ability to build strong relationships with investigators and site staff.
• Problem-Solving: A proactive approach to identifying and resolving issues while maintaining a high level of attention to detail.
• Adaptability: The ability to work effectively in a fast-paced and dynamic environment, managing multiple priorities with precision.

What ICON Can Offer You
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our Benefits Examples Include

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs
• Competitive retirement planning offerings to maximise savings and plan with confidence for the years ahead
• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others

Visit our careers website to read more about the benefits of working at ICON:

At ICON, diversity, inclusion & belonging are fundamental to our culture and values. Our rich diversity makes us more innovative which helps us better serve our people, patients, customers, and our communities. We're proud of our diverse workforce and the work we've done to become a more inclusive organisation. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know through the form below.

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Clinical Research Associate - Johannesburg

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative treatments and therapies.

What You Will Be Doing

• Conducting site qualification, initiation, monitoring, and close-out visits for clinical trials.
• Ensuring protocol compliance, data integrity, and patient safety throughout the trial process.
• Collaborating with investigators and site staff to facilitate smooth study conduct.
• Performing data review and resolution of queries to maintain high-quality clinical data.
• Contributing to the preparation and review of study documentation, including protocols and clinical study reports

Your profile

• Bachelor's degree in a scientific or healthcare-related field.
• Minimum of 2 years of experience as a Clinical Research Associate.
• In-depth knowledge of clinical trial processes, regulations, and ICH-GCP guidelines.
• Strong organizational and communication skills, with attention to detail.
• Ability to work independently and collaboratively in a fast-paced environment.
• Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver's license

What ICON Can Offer You
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our Benefits Examples Include

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply

CAPRISA is an award-winning global research organisation located on the campus of the Nelson R Mandela School of Medicine in Durban, South Africa and undertakes research in HIV, TB and Covid at four clinical research sites in KwaZulu-Natal. CAPRISA's goal is to undertake globally relevant and locally responsive research that contributes to understanding HIV Vaccines and Pathogenesis, Prevention and Epidemiology, the links between Tuberculosis and AIDS treatment and Covid-19. CAPRISA is a UNAIDS Collaborating Centre for HIV Research and Policy and is recognised as a DSI-NRF Centre of Excellence in HIV Prevention and hosts the SAMRC HIV-TB Pathogenesis and Treatment Research Unit.

The successful incumbent will join the CAPRISA Gates Foundation Vaginal Microbiome Clinical Trials Unit (VM-CTU) and will be based at the CAPRISA Headquarters in Durban.

• A bachelor's degree in a health-related or life sciences discipline (e.g., Pharmacy, Nursing, Medical Sciences, Clinical Research, or equivalent).
• At least 2–3 years of experience monitoring clinical trials with knowledge of clinical trials operations, preferably early-phase (Phase I/II) studies.
• Solid knowledge of SA GCP guidelines, ICH-GCP guidelines, South African Ethics in Health Research Guidelines, SAHPRA and international regulatory requirements.
• Prior experience in monitoring and/or trial coordination, within an academic or as a CRA in industry-sponsored trial setting.
• Strong understanding of investigational product accountability, safety reporting, and protocol compliance.
• Proficiency in MS Office (Word, Excel, PowerPoint, Outlook) and familiarity with electronic data capture (EDC) systems.
• Experience working within a multidisciplinary research environment is an advantage.

• Assume the role of regional monitor for all trials conducted in the VM-CTU for an estimated 5 trials per annum.
• Develop and maintain Standard Operating Procedures relevant to the portfolio.
• Create trial monitoring plans in conjunction with the trial sponsor representatives.
• Conduct study initiation visits for each new trial protocol to assess site readiness for study activation.
• Conduct trial monitoring (clinic, laboratory and pharmacy) to ensure compliance with study protocols, SOPs, ICH-GCP, and local regulatory requirements.
• Review case report forms (CRFs), source documents, and data entry to verify accuracy, completeness, and timeliness.
• Monitor and track protocol deviations, adverse events (AEs/SAEs), and data queries.
• Review essential study documentation, including trial master file (eTMF) and investigator site file (eISF).
• Prepare monitoring reports, progress updates, and assist with audits and inspection preparation.
• Contribute to quality assurance initiatives and continuous improvement of trial conduct at the unit.
• Support close-out activities, ensuring data integrity and regulatory compliance are maintained throughout the trial lifecycle.

Role Description

This is a full-time, on-site role for a Clinical Research Associate based in Durban. The Clinical Research Associate will oversee the daily operations of clinical trials, ensure compliance with protocols, and manage research activities. Responsibilities include coordinating with clinical trial sites, monitoring the progress of studies, and maintaining accurate documentation. The role involves close collaboration with other clinical research professionals to ensure the integrity and quality of the research data.

Responsibilities:

• Assume the role of regional monitor for all trials conducted in the VM-CTU for an estimated 5 trials per annum.
• Develop and maintain Standard Operating Procedures relevant to the portfolio.
• Create trial monitoring plans in conjunction with the trial sponsor representatives.
• Conduct study initiation visits for each new trial protocol to assess site readiness for study activation.
• Conduct trial monitoring (clinic, laboratory and pharmacy) to ensure compliance with study protocols, SOPs, ICH-GCP, and local regulatory requirements.
• Review case report forms (CRFs), source documents, and data entry to verify accuracy, completeness, and timeliness.

Qualifications

• A bachelor's degree in a health-related or life sciences discipline (e.g., Pharmacy, Nursing, Medical Sciences, Clinical Research, or equivalent).
• At least 2–3 years of experience monitoring clinical trials with knowledge of clinical trials operations, preferably early-phase (Phase I/II) studies.
• Solid knowledge of SA GCP guidelines, ICH-GCP guidelines, South African Ethics in Health Research Guidelines, SAHPRA and international regulatory requirements.
• Prior experience in monitoring and/or trial coordination, within an academic or as a CRA in industry-sponsored trial setting.
• Strong understanding of investigational product accountability, safety reporting, and protocol compliance.
• Proficiency in MS Office (Word, Excel, PowerPoint, Outlook) and familiarity with electronic data capture (EDC) systems.
• Experience working within a multidisciplinary research environment is an advantage.

Position
: Clinical Research Nurse

Location:
Bloemfontein – Office based

Job Type:
Full-time

Division:
Clinic

Closing date:
19 September 2025

About Us:

Are you ready to be part of a pioneering force in clinical research? With a rich history dating back to 1974, FARMOVS has been at the forefront of accelerating product development through innovative ICH GCP compliant phase 1-2a clinical trials. Having conducted over 3000 trials at our esteemed facility, we offer unmatched expertise and experience in the field.

At FARMOVS, we pride ourselves on our extensive capabilities, including a GLP certified bioanalytical laboratory, registered pharmacy, and a cutting-edge 98-bed clinic equipped with an ISO 15189 accredited clinical laboratory.

Together, we are pushing the boundaries of medical science and improving lives through groundbreaking clinical research. We collaborate with top-tier institutions and sponsors to conduct clinical trials that pave the way for new treatments and therapies.

Located on the vibrant campus of the University of the Free State in Bloemfontein, central South Africa, FARMOVS offers a dynamic and stimulating work environment.

Position overview:

Are you a compassionate, detail-oriented nursing professional with a passion for advancing healthcare? Then this is the job for you We are seeking a skilled Clinical Research Nurse to join our dynamic team at FARMOVS. A Clinical Research Nurse plays a pivotal role in the healthcare and research sector by coordinating and managing clinical trials according to clinical study protocols, South African and ICH GCP Guidelines and SOPs and ensuring the integrity of the research process while prioritizing patient care.

What we are looking for:

Key Accountabilities:

• Review protocol, Clinical Report Form (CRF) and other related functions (e.g. data transcribing).
• Assist in the recruitment of Trial participants,
• Preparation for execution of studies (e.g. prepare source data), screening and execution of studies.
• Ensure accurate collection, recording, and reporting of trial data in compliance with ethical and regulatory standards.
• Support and educate participants about clinical trials while safeguarding their rights and wellbeing.
• Perform verification and operational QC procedures.
• Working on nominated projects / ad hoc project work and any other protocol specific procedures applicable for which training is given.
• Willing to work flexible hours in terms of day shift and possible night shift hours.

Skills:

• Thorough knowledge of applicable international and local guidelines and regulations (e.g. South African & ICH GCP), SOP's and Basic Life Support;
• Excellent interpersonal, verbal and written communication skills;
• Ability to manage multiple and varied tasks with enthusiasm and prioritize workload with attention to detail;
• Ability to motivate volunteers to be reliable and responsible whilst participating in trials;
• Self-motivated with a willingness to accept responsibility and challenges;
• Ability to work in a team and have a flexible attitude;
• Computer skills; ability to use MS Word, Excel, Outlook;
• Accurate execution of protocol related procedures;
• Able to work independently and with initiative.

Education and Experience:

• B Degree/Diploma in nursing
• Registration with SANC
• Current BLS or ACLS certification
• 2 years' experience as a registered nurse

Why Join Us?

At FARMOVS, you will be part of a collaborative team working on innovative projects that make a real difference. We value teamwork, quality, and a commitment to excellence. If you are ready to take on new challenges and grow your career in Information Technology in the Clinical research environment, we would love to hear from you

How to Apply:

If you are eager to contribute to groundbreaking clinical research and interested in joining our dynamic team, please send your CV to and we will contact you. Should you not receive a personal response from us within two to three weeks after the closing date of the vacancy, you can consider your application to have been unsuccessful.

FARMOVS is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.