What Clinic Operations Jobs are in South Africa?

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
Are you ready to lead strategic country operations and drive the effective execution of a life-changing clinical development portfolio? As the Clinical Operations Country Head for South Africa, you will lead a dedicated leadership team to achieve country-specific strategic objectives while ensuring absolute compliance, resource efficiency, and continuous operational improvement.
This role will be based in Midrand, Johannesburg.
**In this vital role, you will:**
* Provide Strategic Leadership: Lead the Country Leadership Team across key therapeutic and operational pillars to ensure cohesive decision-making and optimal portfolio delivery aligned with global strategies.
* Drive Operational Excellence: Oversee the country-level clinical portfolio, actively managing resource allocation, budgets, and data-driven performance optimizations to enhance efficiency and productivity.
* Manage Strategic Partnerships: Serve as the primary driver of strong, collaborative relationships with Clinical Research Organizations (CROs), identifying process improvements and resolving complex operational vendor issues.
* Influence the Local Ecosystem: Build and sustain meaningful networks with external stakeholders, including local Health Authorities, Ethics Committees, and Industry Groups, to advance local clinical research environments.
* Cultivate Top Talent: Inspire, motivate, and mentor a high-performing team, driving department-wide engagement by championing a deeply rooted culture of collaboration, inclusivity, and personal growth.
**Who You Are**
You are a visionary and empathetic leader who thrives in a dynamic environment and is passionate about shaping the future of healthcare. You balance a strategic mindset with strong execution skills and bring an empowering approach to people management.
To be successful in this role, you bring:
* Education: A University degree (BA/BS, MA/MS, PhD, or MD) in life sciences or a related field.
* Experience: 10+ years of robust experience within the pharmaceutical or clinical research industry, showcasing a deep understanding of end-to-end clinical trial processes and international regulations.
* Strategic & Analytical Mindset: Proven proficiency in strategic planning, logical analysis, resource optimization, and the ability to navigate dynamic, evolving environments.
* Empowering Leadership: Demonstrated success in managing, coaching, and developing talent, with a commitment to fostering inclusive behaviors and removing barriers to growth for your team.
* Exceptional Collaboration & Communication: Fluency in English with outstanding interpersonal skills to build trust and influence diverse internal networks and external institutional stakeholders.
Let's thrive together in a culture built on trust, collaboration, respect, and high performance.
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

About the Role Our client, a fast-growing pharmaceutical research organization, is seeking a diligent and organized Clinical Operations Specialist to support the execution of clinical trials in **Port Elizabeth, Eastern Cape**. This role is integral to ensuring that clinical studies are conducted according to protocol, Good Clinical Practice (GCP) guidelines, and regulatory requirements. You will assist in site selection, initiation, monitoring, and close-out activities, working closely with Clinical Research Associates (CRAs) and study sites. This hybrid position offers a mix of office-based work in **Port Elizabeth, Eastern Cape**, and remote flexibility, allowing for efficient management of trial operations. Your contribution will be vital in bringing new therapeutic innovations to patients. Key Responsibilities

• Assist in the preparation and distribution of essential trial documents, including Investigator Site Files (ISFs) and Trial Master Files (TMFs).
• Support the recruitment and selection of clinical trial sites and investigators.
• Prepare and distribute study-related materials to investigative sites.
• Assist in the conduct of site initiation, interim monitoring visits, and site closure activities, as directed by the CRA or Project Manager.
• Help ensure compliance with protocols, Standard Operating Procedures (SOPs), and regulatory guidelines at study sites.
• Track site progress, manage data queries, and ensure timely data entry.
• Coordinate the shipment of investigational products and supplies to clinical sites.
• Act as a liaison between study sites, the clinical operations team, and other departments.
• Maintain accurate and up-to-date study documentation and databases.

Requirements

• Bachelor's degree in a life science, nursing, or related healthcare field.
• 1-3 years of experience in clinical trial coordination or clinical operations support within the pharmaceutical industry or a CRO.
• Familiarity with ICH-Good Clinical Practice (GCP) guidelines and regulatory requirements.
• Proficiency in clinical trial management systems (CTMS) and electronic data capture (EDC) systems.
• Excellent organizational skills and attention to detail.
• Strong written and verbal communication skills.
• Ability to manage multiple tasks and prioritize effectively.
• Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint).
• Team player with the ability to work effectively both independently and as part of a remote/hybrid team.

Benefits Our client offers a competitive salary and benefits package, including health insurance and a retirement savings plan. The role provides excellent opportunities for professional development and training in clinical research, with potential for career advancement within clinical operations. This hybrid role based in **Port Elizabeth, Eastern Cape**, combines the advantages of structured office work with the flexibility of remote engagement, fostering a productive and balanced work environment.

About the Role Our client, a leading pharmaceutical research organization, is seeking an experienced and dynamic Clinical Operations Manager to oversee clinical trial execution in the Soweto region. This pivotal role will be responsible for the efficient and compliant management of clinical trial sites, ensuring adherence to timelines, budgets, and regulatory standards. You will lead a team of clinical research associates (CRAs) and clinical trial assistants (CTAs), providing guidance and support to ensure high-quality trial conduct. This position requires a deep understanding of clinical operations, project management, and regulatory affairs within the pharmaceutical industry. Working in our Soweto office, you will collaborate closely with internal departments such as data management, biostatistics, and regulatory affairs. We are dedicated to advancing medical research and offer a challenging and rewarding environment where your leadership skills will be instrumental in bringing new therapies to patients. This is a fantastic opportunity to drive operational excellence in clinical research.

Key Responsibilities

• Oversee and manage the day-to-day operations of multiple clinical trials at assigned sites.
• Lead, train, and mentor a team of Clinical Research Associates (CRAs) and other clinical operations staff.
• Ensure compliance with Good Clinical Practice (GCP), ICH guidelines, and all applicable local and international regulations.
• Manage clinical trial budgets and timelines, ensuring projects are delivered on schedule and within budget.
• Develop and implement clinical trial site monitoring plans.
• Oversee site selection, initiation, monitoring, and close-out activities.
• Liaise with investigators, site staff, and study sponsors to ensure effective communication and problem resolution.
• Manage vendor relationships and oversight as required.
• Contribute to the development of clinical operational strategies and process improvements.

Requirements

• Bachelor's degree in a life science, nursing, or health-related field; Master's degree preferred.
• Minimum of 5-7 years of experience in clinical operations management within the pharmaceutical industry or a CRO.
• Proven experience in managing clinical trials from initiation to close-out.
• Strong knowledge of GCP, ICH guidelines, and regulatory requirements.
• Demonstrated leadership and team management skills.
• Excellent project management, organizational, and problem-solving abilities.
• Strong communication and interpersonal skills.
• Ability to travel to clinical trial sites as needed.
• Experience with electronic data capture (EDC) systems and clinical trial management systems (CTMS).

Benefits

• Competitive salary package and performance-based incentives.
• Comprehensive medical aid and retirement fund benefits.
• Generous annual leave and paid time off.
• Opportunities for professional development and career advancement.
• A dynamic and supportive work environment in Soweto .
• Be part of a team making a significant contribution to advancing healthcare.

Senior Clinical Data Science Programmer (Clinical SAS Listings)
ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
Are you an experienced **Clinical SAS Listings Programmer** with 3+ years of experience developing and maintaining clinical study listings looking for your next opportunity?
ICON is growing and we're looking for talented professionals to join our Clinical Data Science team in a fully remote role. This is an exciting opportunity for an experienced programmer with strong expertise in **Clinical Study Listings, including DM Listings and Reconciliation Listings** , to work in a client-facing role and deliver high-quality clinical data science and programming solutions that support clinical development programmes across a global portfolio.
**What You Will Be Doing**
+ Develop, validate, and maintain Clinical Study Listings, including DM Listings, Reconciliation Listings, and other study-specific listings.
+ Ensure study listings are configured, delivered, and maintained in line with agreed timelines and quality expectations.
+ Manage clinical study listings in compliance with clinical standards to support the successful execution of clinical trials.
+ Serve as the subject matter expert for Clinical Study Listings, providing support, troubleshooting, and maintenance activities.
+ Partner directly with stakeholders, providing technical expertise and acting as a key contact for programming-related activities.
+ Participate in client meetings, delivering updates, presenting outputs, and supporting decision-making throughout the study lifecycle.
+ Provide guidance on programming best practices, coding standards, validation approaches, and data quality controls.
**You Will Have/Be**
+ Bachelor's degree in Life Sciences, Computer Science, Statistics, or a related discipline.
+ Minimum 3 years of experience developing, validating, and maintaining Clinical SAS Listings.
+ Demonstrated experience producing DM Listings, Reconciliation Listings, and other clinical study listings.
+ Strong proficiency in SAS and experience with programming languages such as R, Rave Custom Functions, and Python.
+ Understanding of CDISC standards and clinical reporting best practices.
+ Excellent verbal and written communication skills.
+ Ability to work independently in a remote environment while managing multiple priorities and deadlines.
\#LI-RD1
**What ICON can offer you:**
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
+ Various annual leave entitlements
+ A range of health insurance offerings to suit you and your family's needs.
+ Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
+ Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
+ Life assurance
+ Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site ( to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here ( in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless - there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here ( to apply

Clinical Data Risk Analyst
ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
As a Clinical Data Risk Analyst at ICON, you will identify and mitigating risks associated with clinical trial data. You will contribute to the overall success of our clinical programs by employing risk assessment methodologies to ensure data integrity and compliance with regulatory standards.
**What You Will Do:**
Your role will involve delivering clinical research work to a high standard, working closely with your team and stakeholders.
Key responsibilities include:
+ Conducting risk assessments on clinical trial data to identify potential issues and recommend mitigation strategies.
+ Collaborating with cross-functional teams to develop and implement risk management plans and protocols.
+ Monitoring data quality and integrity throughout the trial process, reporting findings to stakeholders.
+ Utilizing statistical analysis and visualization tools to communicate risk-related insights effectively.
+ Supporting the preparation of risk management documentation for regulatory submissions and audits.
**Your Profile:**
You will bring relevant clinical research experience, along with the following qualifications and skills.
Required qualifications and experience:
+ Degree in statistics, life sciences, or a related field.
+ 3 years experience in within a clinical research environment.
+ Strong analytical and technical skills.
+ Attention to detail and a proactive approach to identifying and addressing data risks.
+ Effective communication skills, with the ability to collaborate across diverse teams and convey complex information clearly.
\#LI-RD1
**What ICON can offer you:**
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
+ Various annual leave entitlements
+ A range of health insurance offerings to suit you and your family's needs.
+ Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
+ Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
+ Life assurance
+ Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site ( to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here ( in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless - there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here ( to apply

We are looking for a motivated and clinically confident Dietitian to join our hospital-based team, working mainly across Life Hilton Hospital and Lenmed Hospital, as well as surrounding units.

The role involves providing high-quality clinical nutrition care to a wide range of patients, including ICU, surgical, medical, nephrology, elderly care, oncology, and metabolic disease patients. The Dietitian will be expected to assess patients, develop appropriate nutrition care plans, monitor progress, and communicate clearly with doctors, nursing staff, patients, and families.

The candidate will work closely within the multidisciplinary team, including participation in regular ICU MDT ward rounds, ensuring that nutrition forms an active and valuable part of patient management.

Key responsibilities include:

• Nutritional assessment and management of hospital inpatients.

• ICU nutrition support, including enteral and parenteral nutrition considerations.

• Management of surgical, medical, nephrology, geriatric, and metabolic disease patients.

• Clear communication with doctors, nurses, patients, and families.

• Participation in MDT discussions and ICU ward rounds.

• Accurate documentation, follow-up, and continuity of patient care.

• Building strong professional relationships with referring doctors and hospital teams.

• Promoting excellent patient-centered nutrition care across the hospitals.

Requirements & Qualifications:

• Bachelor’s or Master’s degree in Nutrition & Dietetics or related field

• Registered Dietician with HPCSA

• Minimum 3-5 years of clinical experience 

• Strong communication, teamwork, and counselling skills

• Must have own vehicle and valid license - NB

The ideal candidate should be professional, compassionate, organised, clinically curious, and comfortable working in a busy hospital environment. Strong communication skills and the ability to work well within a multidisciplinary team are essential.

As part of our commitment to developing clinical excellence, the successful Dietitian will receive additional clinical training through Critical Point, facilitated by Dr Lauryn Hill. This training covers critical care nutrition, nephrology nutrition, and surgical nutrition. Upon completion, the Dietitian will become accredited through Critical Point as a Dietitian who has received advanced clinical training. The full cost of this training is borne by the practice as part of our commitment to upskilling our clinical team and enhancing the level of care provided to our patients.

This is a valuable opportunity for a Dietitian who wants to grow in the hospital clinical nutrition space and be part of a dynamic, supportive private practice team.

**IQVIA is growing! Hiring multiple Clinical Data Management (CDM) Leads across our FSP (Functional Service Provider) and Traditional (Sponsor-Agnostic) delivery models.**
**Apply now and have your resume considered for Lead Data Manager opportunities across multiple teams - allowing us to match you with the best-fit project and client environment for your experience and interests!**
IQVIA is seeking experienced Clinical Data Management Leads to oversee end-to-end data management delivery for global clinical trials. You'll ensure quality, accuracy, and compliance while leading cross-functional teams that help bring new therapies to life. _This is a remote/WFH position with all necessary equipment provided._
**What You'll Do**
+ Lead data management for complex, global clinical trials from study setup to database lock.
+ Serve as the main client contact for all data management deliverables.
+ Oversee SAE, PK, and external data reconciliation and database deployment.
+ Manage timelines, budgets, and resource allocation to meet customer expectations.
+ Mentor junior data management staff and promote best practices.
+ Drive process improvements and ensure regulatory and SOP compliance.
**Who We're Looking For**
Ideal candidates will have.
+ Bachelor's degree in life sciences, health, clinical, biological, or mathematical field.
+ No less than 10 years of direct clinical data management experience, with 5+ years in a Lead Clinical Data Management role.
+ Your previous roles/job titles may include _Clinical Data Manager, Senior Clinical Data Manager, Lead Data Manager, Principal Data Manager, and/or Data Management Project Manager_ .
+ Proven success managing large global studies (1000+ patients).
+ Expertise with Medidata Rave, Oracle InForm, or similar EDC systems.
+ Strong understanding of GCP, ICH, and clinical research processes.
+ Excellent communication and leadership skills.
**What IQVIA Offers**
+ Fully remote role - company equipment provided
+ Competitive salary and performance-based incentives
+ Career growth and learning opportunities through mentoring and internal mobility
+ Inclusive, global culture focused on innovation and collaboration
**What to Expect After Applying**
+ Recruiter video chat (20 min)
+ Hiring manager interview (1 hour, MS Teams - Offer decisions are typically made within one or two weeks of the final interview.)
**Apply now to join IQVIA, where your expertise shapes the future of data-driven healthcare!**
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create connections that accelerate the development and commercialization of innovative medical treatments. Everything we do is part of a journey to improve patient outcomes and population health worldwide.
To get there, we seek out diverse talent with curious minds and a relentless commitment to innovation and impact. No matter your role, everyone at IQVIA contributes to our shared goal of helping customers improve the lives of patients everywhere. Thank you for your interest in growing your career with us.
EEO Minorities/Females/Protected Veterans/Disabled

**Our values**
+ We believe in applying scientific rigor to reveal the full promise inherent in data.
+ We nurture intellectual curiosity and encourage everyone to approach new challenges with enthusiasm and the desire for discovery.
+ We believe in collaboration and invite a diversity of perspectives, drawing on a variety of talents to create a wealth of possibilities.
+ We prize innovation and seek intelligent solutions using leading-edge technology.
1.Supports cross-functional study team and RBQM Leads in Protocol Risk Assessment, risk identification, and evaluation into Risk MAP.
2. Support RBQM Leads in selection and implementation of Key Risk Indicators (KRIs), and Quality Tolerance Limit parameters (QTLs) and other applicable assessments and dashboards, conducting end of trial summarization of risk management activities for inclusion to Clinical study report.
3. Drafts and oversee RBQM system set up specifications.
4. Perform the execution and review of the Study's assessments and analysis, and diagnosing and explaining anomalies identified in the data and risks.
5. Raise signal and issues in RBQM systems and raise actions as appropriate in RBQM system.
6. Delivers timely high-quality analytics and supporting RBQM leads in communication to the cross-functional study team to identify resolution.
7. Collaborate with assigned programmer to implement study-specific KRIs, QTLs, visualizations, and other analytics in the RBQM system.
8. Perform QC study setup in RBQM system vs RBQM system specifications, if required.
9. Act as RBQM programmer on set up of KRIs, QTLs, data quality assessments as well as visualizations in the RBQM system, if required.
10. Perform the maintenance of the Risk-Based Quality Management (RBQM) system based on RBQM Plan requirements, data sources and structure.
11. Ensure appropriate status and process documentation are produced and maintained during the study.
12. Communicate and/or escalate serious risks and issues to the RBQM Lead, study team and/or management and Quality, as needed.
13. Ensure inspection readiness for clinical risk management and centralized monitoring activities.
Proven experience in a clinical research environment, with experience in a pharmaceutical/biologics/biotechnology company.
Working knowledge of clinical development processes, understanding concepts and principles of study design, conduct and close out, as well as clinical program develop, and knowledge of clinical trials risk management concepts and principles in the Pharma or CRO industry.
Experience and understanding of Risk Based Monitoring system preferred.
Experience with data analytics and data visualization technologies.
Strong critical thinking and analytical skills and aptitude for data analytics including mathematical and statistical concepts.
High degree of accuracy and attention to detail.
Experience and understanding of clinical trial data from various sources (e.g., Clinical devices, SDTM, RAVE, IRT, etc).
Ability to work collaboratively in a team environment whilst managing changing priorities to achieve goals/targets.
Excellent English oral and written communication skills.
Cytel Inc. is an Equal Employment / Affirmative Action Employer. Applicants are considered for all positions without regard to race, color, religion, sex, national origin, age, veteran status, disability, sexual orientation, gender identity or expression, or any other characteristics protected by law.

NOW HIRING: Clinical Facilitator
Join Our Dynamic Healthcare/Nursing Recruitment Agency Team

We are seeking a passionate, experienced, and motivated Clinical Facilitator in the Northern Suburbs to join our growing Healthcare Recruitment Agency. This role is ideal for a healthcare professional who is committed to clinical excellence, staff development, and quality patient care.

Key Responsibilities:

• Facilitate clinical training, induction, and orientation programmes for healthcare staff
• Provide ongoing mentorship, coaching, and support to nursing and care personnel
• Ensure compliance with healthcare standards, policies, and procedures
• Conduct clinical assessments, competency evaluations, and risk assessments
• Support the recruitment, onboarding, and placement of agency healthcare professionals
• Maintain accurate training records, reports, and clinical documentation
• Conduct client visits at private hospitals and public healthcare facilities.
• Promote excellent patient care and professional practice standards
• Build and maintain strong client and staff relationships
• Work effectively with modern healthcare CRM systems and reporting platforms

Minimum Requirements:

• Registered Nurse qualification (SANC registered preferred)
• Proven experience in clinical facilitation or nursing education
• Strong leadership, communication, and interpersonal skills
• Excellent knowledge of healthcare regulations and best practices
• Ability to work independently and within a multidisciplinary team
• Computer literacy and report-writing skills
• Recruitment agency experience is preferable
• Must have a valid Code EB drivers license
• Flexible working hours

If you are passionate about empowering healthcare professionals and improving patient outcomes, we would love to hear from you.