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• Design and execute efficient and scalable synthetic routes for complex organic molecules.
• Perform multi-step organic synthesis and purification techniques.
• Characterize synthesized compounds using a variety of spectroscopic and analytical methods (e.g., NMR, MS, IR, HPLC).
• Troubleshoot synthetic challenges and optimize reaction conditions.
• Conduct literature searches and evaluate new synthetic methodologies.
• Collaborate with process chemists to facilitate the scale-up of promising compounds from lab to pilot plant.
• Maintain detailed and accurate laboratory records and prepare technical reports.
• Ensure compliance with all safety regulations and laboratory best practices.
• Mentor junior chemists and provide technical guidance.
• Contribute to intellectual property generation through patent applications.

• Ph.D. in Organic Chemistry or a related field.
• A minimum of 5 years of post-doctoral or industrial experience in organic synthesis.
• Demonstrated expertise in modern organic synthesis techniques, including asymmetric synthesis and catalysis.
• Proficiency in compound characterization techniques (NMR, MS, HPLC).
• Strong understanding of reaction mechanisms and stereochemistry.
• Experience with scale-up chemistry is a significant advantage.
• Excellent problem-solving skills and a creative approach to synthetic challenges.
• Strong written and verbal communication skills.
• Ability to work independently and collaboratively within a research team in Port Elizabeth .
• Commitment to safety and a proactive approach to risk management.

• Competitive salary and performance-based bonus opportunities.
• Comprehensive medical, dental, and vision insurance.
• Retirement savings plan with company matching.
• Generous paid time off and holidays.
• Opportunities for professional development, including conferences and training.
• Access to advanced synthesis and analytical laboratory equipment.
• A collaborative and innovative research environment.
• Hybrid work flexibility to support work-life balance.

Our client, a globally recognized leader in pharmaceutical research and development, is seeking a highly experienced and innovative Principal Research Chemist to join their esteemed organization in Rustenburg, North West . This senior position is crucial for driving the discovery and synthesis of novel drug candidates. The role involves leading complex organic synthesis projects, developing innovative synthetic routes, and contributing significantly to the early-stage drug discovery pipeline. The ideal candidate will possess exceptional expertise in synthetic organic chemistry, a deep understanding of medicinal chemistry principles, and a passion for advancing healthcare through scientific excellence. This position offers a remarkable chance to work at the forefront of pharmaceutical innovation within a collaborative and intellectually stimulating environment. The role is fully remote, allowing top-tier talent to contribute from anywhere.

• Lead the design and execution of complex multi-step organic synthesis projects to generate novel small molecule drug candidates.
• Develop and optimize innovative synthetic methodologies and reaction conditions to improve efficiency and yield.
• Apply expertise in medicinal chemistry to guide the design of molecules with desired pharmacokinetic and pharmacodynamic properties.
• Characterize synthesized compounds using advanced analytical techniques (NMR, MS, HPLC, etc.) and interpret spectral data.
• Collaborate effectively with biologists, pharmacologists, and other chemists to advance drug discovery programs.
• Troubleshoot synthetic challenges and devise creative solutions to overcome obstacles.
• Mentor and provide technical guidance to junior chemists and research associates.
• Author comprehensive research reports, contribute to patent applications, and prepare manuscripts for publication in peer-reviewed journals.
• Maintain a high level of productivity and manage multiple projects concurrently.
• Stay abreast of the latest advancements in synthetic organic and medicinal chemistry.

• Ph.D. in Organic Chemistry or Medicinal Chemistry.
• Minimum of 10 years of relevant experience in pharmaceutical or biotechnology R&D, with a significant portion focused on synthetic organic chemistry.
• Proven track record of successful synthesis of complex organic molecules and a strong understanding of stereoselective synthesis.
• Extensive experience with a wide range of modern synthetic techniques and reagents.
• Proficiency in spectroscopic and chromatographic analytical techniques for compound characterization.
• Deep understanding of structure-activity relationships (SAR) and structure-property relationships (SPR).
• Demonstrated ability to lead research projects independently and work effectively in a team-oriented environment.
• Excellent written and verbal communication skills, with strong presentation abilities.
• Experience with computational chemistry tools and databases is a plus.
• A strong publication record and/or patent filings are highly valued.

Our client provides a highly competitive compensation package, including a substantial base salary, bonus potential, and stock options. Comprehensive health, dental, and vision insurance are provided, along with a generous retirement savings plan and life insurance coverage. This role offers significant opportunities for professional growth, including attendance at leading scientific conferences and access to advanced training programs. The fully remote nature of the role offers unparalleled flexibility and work-life balance. Our client is committed to fostering a culture of innovation and collaboration, providing a stimulating work environment where scientific contributions are recognized and rewarded. Employees also benefit from an employee stock purchase plan.

• Design and execute complex, multi-step organic syntheses of novel small molecules.
• Develop and optimize reaction conditions to improve yields, purity, and efficiency.
• Purify synthesized compounds using techniques such as column chromatography, recrystallization, and preparative HPLC.
• Characterize synthesized compounds using NMR spectroscopy, mass spectrometry, IR spectroscopy, and other relevant analytical techniques.
• Troubleshoot synthetic challenges and devise creative solutions.
• Maintain detailed and accurate laboratory notebooks and experimental records.
• Collaborate effectively with medicinal chemists, biologists, and other team members to advance drug discovery projects.
• Stay abreast of the latest advancements in synthetic organic chemistry and relevant scientific literature.
• Contribute to the preparation of scientific reports, publications, and patent applications.

• Ph.D. in Organic Chemistry, Synthetic Chemistry, or a closely related field.
• Proven experience in modern synthetic organic chemistry methodologies.
• Hands-on experience with a wide range of organic reactions and purification techniques.
• Proficiency in spectroscopic characterization techniques, particularly NMR and mass spectrometry.
• Strong understanding of reaction mechanisms and stereochemistry.
• Excellent problem-solving skills and a detail-oriented approach to research.
• Ability to work independently and manage multiple synthetic projects simultaneously.
• Strong communication and interpersonal skills for effective teamwork.
• Experience in medicinal chemistry or process chemistry is a plus.
• A passion for chemistry and its application in drug discovery.

Role Overview

A leading igaming and betting company is seeking a commercially focused, hands-on BI, Analytics & Data Insights Manager to lead the business intelligence, management information, reporting, and analytics capability across the organization.

This is not a pure enterprise architecture or theoretical governance role. The business already has technical architecture capability in place. The focus of this role is on transforming operational, customer, betting, gaming, financial, and marketing data into meaningful commercial insights that support faster, smarter business decision-making.

The successful candidate must be able to operate both strategically and operationally — engaging with leadership on business performance while also remaining close enough to the data, reporting environment, dashboards, and analytics outputs to ensure accuracy, usability, and commercial value.

This role is ideally suited to someone from an iGaming, sportsbook, online betting, fintech, payments, digital product, telecoms, or other high-volume transactional environments where real-time reporting, operational analytics, and customer behaviour insights are business critical.

Key Focus Areas

Business Intelligence & Reporting

• Own and drive the BI and analytics capability across the business

• Lead the development of operational, commercial, customer, financial, and executive dashboards

• Ensure accurate, trusted, and actionable reporting across all departments

• Deliver meaningful MI (Management Information) that supports strategic and operational decision-making

• Improve visibility of business performance through self-service reporting and analytics

• Standardise KPIs, reporting definitions, and dashboard structures across the organisation

Commercial & Operational Analytics

Drive analytics and reporting across areas including:

• Sportsbook and casino performance

• Customer acquisition, retention, churn, and player behaviour

• CRM and campaign performance analytics

• Revenue, GGR, NGR, bonus spend, and promotional effectiveness

• Deposits, withdrawals, settlements, and payment trends

• Operational and contact centre performance

• Workforce and productivity reporting

• Risk, fraud, AML, and responsible gambling indicators

The role requires someone who can identify trends, risks, opportunities, and operational inefficiencies through data analysis and translate these into commercially valuable insights.

Dashboarding, Visualisation & Data Storytelling

• Design and oversee intuitive, executive-level dashboards and reporting environments

• Ensure reporting is visually clear, commercially relevant, and user-friendly

• Translate complex datasets into simplified business insights for non-technical stakeholders

• Drive dashboard adoption across leadership and operational teams

• Ensure near real-time visibility where operationally required

Data Integrity & Reporting Accuracy

• Ensure consistency and integrity of reporting across betting, operational, finance, and CRM environments

• Work closely with Finance and Operations to reconcile and validate key business metrics

• Improve data quality, reporting reliability, and reporting governance

• Support audit and compliance reporting requirements where needed

• Identify reporting gaps and continuously improve analytics capability

Stakeholder Engagement

Partner closely with:

• Executive leadership

• Operations

• Finance

• Marketing & CRM

• Customer Support

• Compliance & Risk

• Technology teams

The successful candidate must be commercially confident, highly collaborative, and capable of influencing business decisions through data-driven insights.

Technical Environment

Strong experience in several of the following is highly preferred:

• Power BI

• SQL

• Excel / Advanced Excel

• Data visualisation and dashboarding tools

• Data warehousing / reporting environments

• CRM and campaign analytics

• Operational reporting environments

• High-volume transactional databases

• Near real-time reporting

• Data modelling and KPI frameworks

Exposure to cloud analytics environments, customer data platforms, and iGaming reporting ecosystems would be advantageous.

Required Experience

Essential

• 6+ years’ experience in BI, data analytics, reporting, or commercial insights roles

• 3+ years in a senior BI or analytics management role

• Experience within high-volume transactional environments

• Strong hands-on dashboarding and reporting capability

• Strong commercial analytics and business performance reporting experience

• Advanced SQL and BI reporting exposure

• Experience working with operational, financial, customer, or digital performance data

Highly Advantageous

• iGaming, sportsbook, online betting, fintech, telecoms, or payments industry experience

• Experience analysing customer/player behaviour and transactional data

• Exposure to fraud, AML, responsible gambling, or risk analytics

• Experience building reporting functions or BI capability within growing businesses

Personality & Working Style

The company is looking for someone who is:

• Commercially sharp and analytically strong

• Strategic but still hands-on

• Naturally curious and insight-driven

• Strong with detail and reporting accuracy

• Calm in fast-paced operational environments

• Able to communicate confidently with executives and operational teams alike

• Passionate about using data to improve performance, efficiency, and customer experience

Why This Role Is Exciting

This is an opportunity to build and shape the BI and analytics capability within a rapidly growing digital gaming environment where data directly influences customer engagement, operational performance, revenue growth, and strategic decision-making.

The role offers strong visibility across the business and the opportunity to partner directly with leadership in driving a truly data-informed culture.

Overview of responsibilities:

Materials:

• After the first quote is approved, create & check specifications to main contract quote & contract.
• Analyse tender drawings and check for errors, then suggest to draughting department the appropriate changes. For example, details, materials, quantities, etc.
• Take off and measure buildings in great detail in order to get exact material requirements. This is done according to specific measuring spreadsheets.
• Compare costing to material measured in terms of quality vs quality vs cost.
• Compile a comprehensive Material / Loading Schedule of all materials
• Distribute material schedules to purchasing department, site managers & factory.

• Source quotes for sub-contracting items and negotiate on price where possible.
• Ensure Quotes procured are comprehensive in including all of the works required to be executed under the Sub contract
• Ensure sub-contractors are suitably skilled, experienced and qualified to carry out the works required.
• Ensure the terms of appointment are clear to the sub-contractor in terms of Payment schedule, Retentions, Quality and performance required.
• Ensure Sub-contractors are appointed on price within the cost allowable.
• Update and maintain preferred sub-contractor database
• Negotiate with sub-contractors and create purchase orders.
• Source and one-off Sub-Contractors needed for a project or for late notifications.
• Handover relevant documents to Site Manager before or during contracts meeting

• Work to company standards by completing tickets on time at all clients sites.
• Ensure the service and information is scanned and documented on the Pest Management System
• Provide a professional and comprehensive service in line with SOPs
• Supervise and teach PCO assistants and Interns in line with SOP and clients scope of work and/or HACCP standards as required
• Take care of company vehicle and equipment

• Complete daily treatments reports and ensure IPM file is maintained and updated after each service
• Obtain clients signature after service is completed
• Document proofing and housekeeping requirements
• Document all units missing and / or broken

• Apply and implement all safety standards

• Build professional relationships with all stakeholders
• The successful candidate must demonstrate a high level of commitment to customer service, as delivering exceptional service is the branchs top priority and primary focus.